Primary Pure Intrarenal Yolk Sac Tumor in 1.5-Year-Old Boy-A Rare Case Report

被引：3

作者：

Qayoom, Sumaira ^{[1
]}

Shabbir, Nida ^{[1
]}

Singhai, Atin ^{[1
]}

Verma, Nishant ^{[2
]}

Rawat, Shalini ^{[1
]}

机构：

[1] King Georges Med Univ, Dept Pathol, Lucknow 226003, Uttar Pradesh, India

[2] King Georges Med Univ, Dept Paediat, Lucknow, Uttar Pradesh, India

来源：

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2023年 / 31卷 / 07期

关键词：

intrarenal; primary; yolk sac tumor; alpha-fetoprotein; immunohistochemistry; GERM-CELL TUMORS; RENAL NEOPLASMS; WILMS-TUMOR; CHILDHOOD;

D O I：

10.1177/10668969221149131

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Germ cell tumors primarily arise in gonads and extragonadal germ cell tumors, an uncommon entity, originates usually along the midline. Here, we report the fifth example of intrarenal pure yolk sac tumor in a 1.5-year-old boy who presented with abdominal pain and underwent excision of the mass for suspected Wilms tumor. On histopathology and immunohistochemistry, a diagnosis of a yolk sac tumor was rendered. Postoperative serum alpha-fetoprotein levels were 21 000 ng/dl. The purpose of this report is to emphasize the importance of suspecting a germ cell tumor as one of the differential diagnoses of a suspected case of Wilms tumor and the significance of evaluating serum alpha-fetoprotein levels preoperatively.

引用

页码：1381 / 1386

页数：6

共 19 条

[1]

[Anonymous], 2021, Clinicopathological Profile of Cancers in India: A Report of the Hospital Based Cancer Registries

[2] RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases [J].

Cao, Dengfeng ;

Liu, Aijun ;

Wang, Fenghua ;

Allan, Robert W. ;

Mei, Kaiyong ;

Peng, Yan ;

Du, Jun ;

Guo, Shuangping ;

Abel, Ty W. ;

Lane, Zhaoli ;

Ma, Joe ;

Rodriguez, Maria ;

Akhi, Shirin ;

Dehiya, Neha ;

Li, Jianping .

MODERN PATHOLOGY, 2011, 24 (02) :288-296

[3] To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm [J].

De Felici, Massimo ;

Klinger, Francesca Gioia ;

Campolo, Federica ;

Balistreri, Carmela Rita ;

Barchi, Marco ;

Dolci, Susanna .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (11)

[4] Indications and results of diagnostic biopsy in pediatric renal tumors: A retrospective analysis of 317 patients with critical review of SIOP guidelines [J].

de la Monnerave, Yvan ;

Michon, J. ;

Pacquement, H. ;

Aerts, I ;

Orbach, Daniel ;

Doz, F. ;

Bourdeaut, F. ;

Sarnacki, S. ;

Philippe-Chomette, P. ;

Audry, G. ;

Coulomb, A. ;

Freneaux, P. ;

Klranienko, J. ;

Berrebi, D. ;

Zucker, J-M ;

Schleiermacher, G. ;

Brisse, H. J. .

PEDIATRIC BLOOD & CANCER, 2019, 66 (06)

[5]

Huang HY, 2002, ARCH PATHOL LAB MED, V126, P1106

[6] 111 renal neoplasms of childhood:: A clinicopathologic study [J].

Jenkner, A ;

Camassei, FD ;

Boldrini, R ;

De Sio, L ;

Ravà, L ;

Bosman, C ;

Boglino, C ;

Donfrancesco, A .

JOURNAL OF PEDIATRIC SURGERY, 2001, 36 (10) :1522-1527

[7] Intrarenal pure yolk sac tumor: An extremely rare entity [J].

Kumar, Yashwant ;

Bhatia, Alka ;

Kumar, Vijay ;

Vaiphei, Kim .

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2007, 15 (02) :204-206

[8] CT Findings of Intrarenal Yolk Sac Tumor with Tumor Thrombus Extending into the Inferior Vena Cava: A Case Report [J].

Lin, ShaoChun ;

Li, XueHua ;

Sun, CanHui ;

Feng, ShiTing ;

Peng, ZhenPeng ;

Huang, SiYun ;

Li, ZiPing .

KOREAN JOURNAL OF RADIOLOGY, 2014, 15 (05) :641-645

[9] Intrarenal mixed germ cell tumor [J].

Liu, YC ;

Wang, JS ;

Chen, CJ ;

Sung, PK ;

Tseng, HH .

JOURNAL OF UROLOGY, 2000, 164 (06) :2020-2021

[10] Malignant germ cell tumors in childhood: results of the first Italian Cooperative Study "TCG 91" [J].

Lo Curto, M ;

Lumia, F ;

Alaggio, R ;

Cecchetto, G ;

Almasio, P ;

Indolfi, P ;

Siracusa, F ;

Bagnulo, S ;

De Bernardi, B ;

De Laurentis, T ;

Di Cataldo, A ;

Tamaro, P .

MEDICAL AND PEDIATRIC ONCOLOGY, 2003, 41 (05) :417-425

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