New insights into balancing wound healing and scarless skin repair

被引：46
|
作者：
Zhou, Shengxi [1 ]
Xie, Mengbo [1 ]
Su, Jingjing [1 ]
Cai, Bingjie [2 ]
Li, Jingan [3 ,4 ]
Zhang, Kun [1 ,5 ]
机构：
[1] Zhengzhou Univ, Sch Life Sci, Zhengzhou, Henan, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Dermatol, Zhengzhou, Henan, Peoples R China
[3] Zhengzhou Univ, Sch Mat Sci & Engn, Zhengzhou, Henan, Peoples R China
[4] Zhengzhou Univ, Sch Mat Sci & Engn, 100, Sci Rd, Zhengzhou 450001, Henan, Peoples R China
[5] Zhengzhou Univ, Sch Life Sci, Zhengzhou 450001, Henan, Peoples R China
来源：
JOURNAL OF TISSUE ENGINEERING | 2023年 / 14卷
基金：
中国国家自然科学基金;
关键词：
Wound healing; skin regeneration; scar; fibroblasts; extracellular matrix; HYALURONIC-ACID; GROWTH-FACTOR; CHITOSAN HYDROGEL; CELLS; MATRIX; ANTIBACTERIAL; TISSUE; GENE; RECONSTRUCTION; NANOPARTICLES;
D O I：
10.1177/20417314231185848
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Scars caused by skin injuries after burns, wounds, abrasions and operations have serious physical and psychological effects on patients. In recent years, the research of scar free wound repair has been greatly expanded. However, understanding the complex mechanisms of wound healing, in which various cells, cytokines and mechanical force interact, is critical to developing a treatment that can achieve scarless wound healing. Therefore, this paper reviews the types of wounds, the mechanism of scar formation in the healing process, and the current research progress on the dual consideration of wound healing and scar prevention, and some strategies for the treatment of scar free wound repair.
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页数：28
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