Acceleration of sporadic Creutzfeldt-Jakob disease progression by COVID requires evidence from appropriately designed studies

被引：0
作者：
Finsterer, Josef [1 ]
机构：
[1] Neurol & Neurophysiol Ctr, Postfach 20, A-1180 Vienna, Austria
来源：
EGYPTIAN JOURNAL OF NEUROLOGY PSYCHIATRY AND NEUROSURGERY | 2023年 / 59卷 / 01期
关键词：
SARS-CoV-2; COVID-19; Creutzfeldt-Jakob disease; Prion disorder; Neurodegeneration;
D O I：
10.1186/s41983-023-00762-z
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The aim of this letter to the editor is to discuss the influence of SARS-CoV-2 infection on the progression of sporadic Creutzfeldt-Jakob disease (sCJD). A 73-year-old male was diagnosed with sCJD based on the clinical presentation, cerebral MRI, FDG-PET, and elevated 14-3-3 in cerebrospinal fluid. One month earlier he had suffered a slight COVID-19 infection. It was concluded that COVID-19 can lead to accelerated pathogenesis and exaggerated manifestations of sCJD.
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