Prevalence and prognostic impact of the coexistence of cachexia and sarcopenia in older patients with heart failure

被引：16

作者：

Fujimoto, Yudai ^{[1
]}

Maeda, Daichi ^{[2
]}

Kagiyama, Nobuyuki ^{[2
,3
,4
]}

Sunayama, Tsutomu ^{[2
]}

Dotare, Taishi ^{[2
]}

Jujo, Kentaro ^{[5
]}

Saito, Kazuya ^{[6
]}

Kamiya, Kentaro ^{[7
]}

Saito, Hiroshi ^{[2
,8
]}

Ogasahara, Yuki ^{[9
]}

Maekawa, Emi ^{[10
]}

Konishi, Masaaki ^{[11
]}

Kitai, Takeshi ^{[12
,13
]}

Iwata, Kentaro ^{[13
]}

Wada, Hiroshi ^{[1
]}

Hiki, Masaru ^{[2
]}

Kasai, Takatoshi ^{[2
,14
]}

Nagamatsu, Hirofumi ^{[15
]}

Ozawa, Tetsuya ^{[16
]}

Izawa, Katsuya ^{[17
]}

Yamamoto, Shuhei ^{[18
]}

Aizawa, Naoki ^{[19
]}

Wakaume, Kazuki ^{[20
]}

Oka, Kazuhiro ^{[21
]}

Momomura, Shin-ichi ^{[22
]}

Matsue, Yuya ^{[2
,23
]}

机构：

[1] Jichi Med Univ, Saitama Med Ctr, Dept Cardiovasc Med, Saitama, Japan

[2] Juntendo Univ, Dept Cardiovasc Biol & Med, Grad Sch Med, Tokyo, Japan

[3] Sakakibara Heart Inst Okayama, Dept Cardiol, Okayama, Japan

[4] Juntendo Univ, Dept Digital Hlth & Telemed R&D, Tokyo, Japan

[5] Nishiarai Heart Ctr Hosp, Dept Cardiol, Tokyo, Japan

[6] Sakakibara Heart Inst Okayama, Dept Rehabil, Okayama, Japan

[7] Kitasato Univ, Sch Allied Hlth Sci, Dept Rehabil, Sagamihara, Japan

[8] Kameda Med Ctr, Dept Rehabil, Kamogawa, Japan

[9] Sakakibara Heart Inst Okayama, Dept Nursing, Okayama, Japan

[10] Kitasato Univ, Dept Cardiovasc Med, Sch Med, Sagamihara, Japan

[11] Yokohama City Univ, Div Cardiol, Med Ctr, Yokohama, Japan

[12] Natl Cerebral & Cardiovasc Ctr, Dept Cardiovasc Med, Osaka, Japan

[13] Kobe City Med Ctr, Dept Rehabil, Gen Hosp, Kobe, Japan

[14] Juntendo Univ, Cardiovasc Resp Sleep Med, Grad Sch Med, Tokyo, Japan

[15] Tokai Univ, Dept Cardiol, Sch Med, Isehara, Japan

[16] Odawara Municipal Hosp, Dept Rehabil, Odawara, Japan

[17] Matsui Heart Clin, Dept Rehabil, Owariasahi, Japan

[18] Shinshu Univ Hosp, Dept Rehabil, Matsumoto, Japan

[19] Univ Ryukyus, Dept Cardiovasc Med Nephrol & Neurol, Okinawa, Japan

[20] Kitasato Univ, Rehabil Ctr, Med Ctr, Tokyo, Japan

[21] Saitama Citizens Med Ctr, Dept Rehabil, Saitama, Japan

[22] Saitama Citizens Med Ctr, Saitama, Japan

[23] Juntendo Univ, Dept Cardiovasc Biol & Med, Grad Sch Med, 2-1-1 Hongo,Bunkyo Ku, Tokyo 1138421, Japan

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2023年 / 381卷

关键词：

Heart failure; cachexia; Sarcopenia; Prognosis; Older patients; CARDIAC CACHEXIA; RISK-FACTOR; MORTALITY; SURVIVAL; PARADOX; OBESITY; DISEASE;

D O I：

10.1016/j.ijcard.2023.03.035

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: No study with an adequate patients' number has examined the relationship/overlap between sar-copenia and cachexia. We examined the prevalence of the overlap and prognostic implications of sarcopenia and cachexia in older patients with heart failure using well-accepted definitions. Methods: This was a post-hoc sub-analysis of the FRAGILE-HF study, a prospective, multicenter, observational study conducted at 15 hospitals in Japan. In total, 905 hospitalized older patients were classified into four groups based on the presence or absence of cachexia and/or sarcopenia, which were defined according to the Evans and Asian Working Group for Sarcopenia criteria revised in 2019, respectively. The primary endpoint was 2-year all -cause mortality.

引用

页码：45 / 51

页数：7

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