Introduction: This study aimed to determine the relationship of socio-demographic variables (type of residence, age, occupation, level of education, and wealth index) and media exposure variables, with knowledge about human immunodeficiency virus (HIV) among women.Material and methods: It uses secondary data from the 2017 Indonesian demographic and health sur-vey (SKDI) section for fertile age women (WUS). The unit of analysis in this study was households in Indonesia consisting of mothers of reproductive age (range, 15-49 years), with a total sample of 49,627 individuals. Chi-square, correspondence, and t-test analyses were applied.Results: The results of the study indicated that socio-demographic factors, including type of resi-dence, age, occupation, education level, and wealth index, and media exposure variables correlate with knowledge about HIV. However, there are still misconceptions and inaccurate knowledge about HIV among women.Conclusions: This study found that all socio-demographic variables (type of residence, wealth index, educational level, age group, and occupation) and media exposure variables had a significant relationship with knowledge about HIV. The correlation between education level variables and knowledge of HIV is the strongest correlation among other socio-demographic variables.