Combined treatment with venetoclax, dasatinib, and FLT3 inhibitors for NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia: A pediatric case report

被引：10
作者：
Wen, Xiaojia [1 ,2 ,3 ,4 ]
Wu, Ying [1 ,2 ,3 ,4 ]
Huang, Pengli [1 ,2 ,3 ,4 ]
Zheng, Huyong [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Hematol Ctr, Beijing Key Lab Pediat Hematol Oncol, Beijing, Peoples R China
[2] Capital Med Univ, Natl Key Clin Discipline Pediat Hematol, Natl Key Discipline Pediat, Beijing, Peoples R China
[3] Minist Educ, Key Lab Major Dis Children, Beijing, Peoples R China
[4] Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Beijing, Peoples R China
[5] Hematol Ctr, Beijing Key Lab Pediat Hematol Oncol, Beijing 100045, Peoples R China
来源：
PEDIATRIC BLOOD & CANCER | 2023年 / 70卷 / 07期
基金：
北京市自然科学基金;
关键词：
acute myeloid leukemia; dasatinib; FLT3; inhibitors; FLT3-ITD; NUP98-NSD1; venetoclax;
D O I：
10.1002/pbc.30308
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：2
相关论文
共 5 条
[1]   Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial [J].
Jin, Jie ;
Wang, Jian-Xiang ;
Chen, Fei-Fei ;
Wu, De-Pei ;
Hu, Jiong ;
Zhou, Jian-Feng ;
Hu, Jian-Da ;
Wang, Jian-Min ;
Li, Jian-Yong ;
Huang, Xiao-Jun ;
Ma, Jun ;
Ji, Chun-Yan ;
Xu, Xiao-Ping ;
Yu, Kang ;
Ren, Han-Yun ;
Zhou, Yu-Hong ;
Tong, Yin ;
Lou, Yin-Jun ;
Ni, Wan-Mao ;
Tong, Hong-Yan ;
Wang, Hua-Feng ;
Mi, Ying-Chang ;
Du, Xin ;
Chen, Bao-An ;
Shen, Yi ;
Chen, Zhu ;
Chen, Sai-Juan .
LANCET ONCOLOGY, 2013, 14 (07) :599-608
[2]   Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia [J].
Kivioja, Jarno L. ;
Thanasopoulou, Angeliki ;
Kumar, Ashwini ;
Kontro, Mika ;
Yadav, Bhagwan ;
Majumder, Muntasir M. ;
Javarappa, Komal K. ;
Eldfors, Samuli ;
Schwaller, Juerg ;
Porkka, Kimmo ;
Heckman, Caroline A. .
LEUKEMIA, 2019, 33 (06) :1360-1372
[3]   Mutated WT1, FLT3-ITD, and NUP98-NSD1 Fusion in Various Combinations Define a Poor Prognostic Group in Pediatric Acute Myeloid Leukemia [J].
Niktoreh, Naghmeh ;
Walter, Christiane ;
Zimmermann, Martin ;
von Neuhoff, Christine ;
von Neuhoff, Nils ;
Rasche, Mareike ;
Waack, Katharina ;
Creutzig, Ursula ;
Hanenberg, Helmut ;
Reinhardt, Dirk .
JOURNAL OF ONCOLOGY, 2019, 2019
[4]   Single-center pediatric experience with venetoclax and azacitidine as treatment for myelodysplastic syndrome and acute myeloid leukemia [J].
Winters, Amanda C. ;
Maloney, Kelly W. ;
Treece, Amy L. ;
Gore, Lia ;
Franklin, Anna K. .
PEDIATRIC BLOOD & CANCER, 2020, 67 (10)
[5]   Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised phase 3 trial [J].
Xuan, Li ;
Wang, Yu ;
Huang, Fen ;
Fan, Zhiping ;
Xu, Yajing ;
Sun, Jing ;
Xu, Na ;
Deng, Lan ;
Li, Xudong ;
Liang, Xinquan ;
Luo, Xiaodan ;
Shi, Pengcheng ;
Liu, Hui ;
Wang, Zhixiang ;
Jiang, Ling ;
Yu, Chunzi ;
Zhou, Xuan ;
Lin, Ren ;
Chen, Yan ;
Tu, Sanfang ;
Huang, Xiaojun ;
Liu, Qifa .
LANCET ONCOLOGY, 2020, 21 (09) :1201-1212
1