A Case of Eosinophilic Granulomatosis With Polyangiitis (EGPA) Peripheral Neuropathy With Positive Anti-Myelin Oligodendrocyte (MOG) Antibodies

被引:0
作者
Yousuf, Kauser [1 ]
Ibrahim, Hadiza [1 ]
Elbashari, Mahfoud [2 ]
Abouelnaga, Mohamed E. [2 ]
Alzaabi, Amani [2 ]
机构
[1] Zayed Mil Hosp, Internal Med, Abu Dhabi, U Arab Emirates
[2] Zayed Mil Hosp, Neurol Internal Med, Abu Dhabi, U Arab Emirates
关键词
systemic autoimmune diseases; antineutrophil cytoplasmic antibody (anca) associated vasculitis (aav); anti-mog antibody; peripheral neuropathy; eosinophilic granulomatosis with polyangiitis (egpa); AMERICAN-COLLEGE; VASCULITIS;
D O I
10.7759/cureus.48055
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Peripheral neuropathy is a common manifestation of Eosinophilic Granulomatosis with Polyangiitis (EGPA), a rare autoimmune disorder caused by eosinophilic infiltration of multiple organs including the nervous system. Recent research has shown an association between myelin oligodendrocyte glycoprotein (MOG) antibodies and various neurologic conditions. We present a unique case of EGPA with positive MOG antibodies in the cerebrospinal fluid (CSF) in a patient presenting with peripheral neuropathy. We also highlight a few diagnostic dilemmas with EGPA and the importance of early diagnosis and appropriate treatment. Clinical, laboratory, radiological, and electrophysiologic findings are discussed.
引用
收藏
页数:13
相关论文
共 12 条
[1]  
[Anonymous], 2022, Churg-Strauss Disease Workup
[2]  
[Anonymous], 2022, Churg-Strauss Disease
[3]   Peripheral neuropathy in antineutrophil cytoplasmic antibody-associated vasculitides Insights from the DCVAS study [J].
Bischof, Antje ;
Jaeger, Veronika K. ;
Hadden, Robert D. M. ;
Luqmani, Raashid A. ;
Probstel, Anne-Katrin ;
Merkel, Peter A. ;
Suppiah, Ravi ;
Craven, Anthea ;
Collins, Michael P. ;
Daikeler, Thomas .
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 2019, 6 (06)
[4]   MOG-IgG-associated disorder and systemic lupus erythematosus disease: Systematic review [J].
Breis, Leticia Caroline ;
Machado Schlindwein, Marco Antonio ;
Bandeira, Isabelle Pastor ;
Fontana, Thaise Machiavelli ;
Parolin, Laura Fiuza ;
Weingrill, Pedro ;
Kleinpaul Vieira, Rodrigo Goncalves ;
Magno Goncalves, Marcus Vinicius .
LUPUS, 2021, 30 (03) :385-392
[5]   2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis [J].
Chung, Sharon A. ;
Langford, Carol A. ;
Maz, Mehrdad ;
Abril, Andy ;
Gorelik, Mark ;
Guyatt, Gordon ;
Archer, Amy M. ;
Conn, Doyt L. ;
Full, Kathy A. ;
Grayson, Peter C. ;
Ibarra, Maria F. ;
Imundo, Lisa F. ;
Kim, Susan ;
Merkel, Peter A. ;
Rhee, Rennie L. ;
Seo, Philip ;
Stone, John H. ;
Sule, Sangeeta ;
Sundel, Robert P. ;
Vitobaldi, Omar I. ;
Warner, Ann ;
Byram, Kevin ;
Dua, Anisha B. ;
Husainat, Nedaa ;
James, Karen E. ;
Kalot, Mohamad A. ;
Lin, Yih Chang ;
Springer, Jason M. ;
Turgunbaev, Marat ;
Villa-Forte, Alexandra ;
Turner, Amy S. ;
Mustafa, Reem A. .
ARTHRITIS CARE & RESEARCH, 2021, 73 (08) :1088-1105
[6]  
clevelandclinic, 2021, EGPA (formerly Churg-Strauss Syndrome)
[7]   Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort [J].
Comarmond, Cloe ;
Pagnoux, Christian ;
Khellaf, Mehdi ;
Cordier, Jean-Francois ;
Hamidou, Mohamed ;
Viallard, Jean-Francois ;
Maurier, Francois ;
Jouneau, Stephane ;
Bienvenu, Boris ;
Puechal, Xavier ;
Aumaitre, Olivier ;
Le Guenno, Guillaume ;
Le Quellec, Alain ;
Cevallos, Ramiro ;
Fain, Olivier ;
Godeau, Bertrand ;
Seror, Raphaele ;
Dunogue, Bertrand ;
Mahr, Alfred ;
Guilpain, Philippe ;
Cohen, Pascal ;
Aouba, Achille ;
Mouthon, Luc ;
Guillevin, Loic .
ARTHRITIS AND RHEUMATISM, 2013, 65 (01) :270-281
[8]   SYSTEMIC VASCULITIS WITH ASTHMA AND EOSINOPHILIA - A CLINICAL APPROACH TO THE CHURG-STRAUSS-SYNDROME [J].
LANHAM, JG ;
ELKON, KB ;
PUSEY, CD ;
HUGHES, GR .
MEDICINE, 1984, 63 (02) :65-81
[9]   THE AMERICAN-COLLEGE-OF-RHEUMATOLOGY 1990 CRITERIA FOR THE CLASSIFICATION OF CHURG-STRAUSS-SYNDROME (ALLERGIC GRANULOMATOSIS AND ANGIITIS) [J].
MASI, AT ;
HUNDER, GG ;
LIE, JT ;
MICHEL, BA ;
BLOCH, DA ;
AREND, WP ;
CALABRESE, LH ;
EDWORTHY, SM ;
FAUCI, AS ;
LEAVITT, RY ;
LIGHTFOOT, RW ;
MCSHANE, DJ ;
MILLS, JA ;
STEVENS, MB ;
WALLACE, SL ;
ZVAIFLER, NJ .
ARTHRITIS AND RHEUMATISM, 1990, 33 (08) :1094-1100
[10]  
mayoclinic, 2021, Churg-strauss syndrome