Review: Discogenic Back Pain: Update on Treatment

被引:4
|
作者
Remotti, Edgar [1 ]
Nduaguba, Chinoso [1 ]
Woolley, Parker A. [1 ]
Ricciardelli, Ryan [1 ]
Phung, Anh [1 ]
Kim, Rosa [2 ]
Urits, Ivan [3 ]
Kaye, Alan David [4 ,6 ,7 ,8 ,9 ]
Hasoon, Jamal [5 ]
Simopoulos, Thomas [1 ]
Yazdi, Cyrus [1 ]
Robinson, Christopher L. [1 ]
机构
[1] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Anesthesiol Crit Care & Pain Med, Boston, MA USA
[2] Georgetown Univ Hosp, Dept Gen Surg, Medstar, Washington, DC USA
[3] Southcoast Phys Grp, Wareham, MA USA
[4] Louisiana State Univ Shreveport, Dept Anesthesiol, Shreveport, LA USA
[5] UTHlth McGovern Med Sch, Dept Anesthesiol Crit Care & Pain Med, Houston, TX USA
[6] LSU Sch Med, Anesthesiol, 1501 Kings Hwy, Shreveport, LA 71103 USA
[7] LSU Sch Med, Pharmacol Toxicol & Neurosci, 1501 Kings Hwy, Shreveport, LA 71103 USA
[8] LSU Sch Med, Anesthesiol & Pharmacol, New Orleans, LA USA
[9] Tulane Sch Med, Anesthesiol & Pharmacol, New Orleans, LA USA
关键词
Discogenic back pain; chronic lower back pain; discography; biologics; allogeneic disc tissue; INTERVERTEBRAL DISC; VERTEBROGENIC PAIN; CLINICAL-EFFICACY; DIAGNOSIS; DEGENERATION; DISCOGRAPHY; NERVE; SPINE; METAANALYSIS; MECHANISMS;
D O I
10.52965/001c.84649
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Purpose of Review Lower back pain (LBP) has a lifetime prevalence of 80% in the United States population. Discogenic back pain (DBP), a subcategory of LBP, occurs as a result of the interverbal disc degeneration without disc herniation. Diagnosis relies on history, physical exam, and imaging such as MRI, provocative discography, or CT discography. Recent Findings Treatment of DBP involves a multifaceted approach with an emphasis on conservative measures including behavioral modification, pharmacologic management, and other non-pharmacologic interventions with invasive therapy reserved for select patients. Due to the paucity of data on the treatment of DBP, treatment also relies on data derived from treatment of chronic LBP (CLBP). Despite the scarcity of data for the treatment of DBP, treatments do exist with varying efficacy for DBP. Novel techniques such as the use of biologics may provide another avenue for treatment though further studies are needed to better evaluate the most efficacious regimen for both novel and existing treatments.
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页数:12
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