Gestational Diabetes Mellitus and Antenatal Corticosteroid Therapy-A Narrative Review of Fetal and Neonatal Outcomes

被引：3

作者：

Babovic, Ivana R. ^{[1
,2
]}

Dotlic, Jelena ^{[1
,2
]}

Sparic, Radmila ^{[1
,2
]}

Jovandaric, Miljana Z. ^{[3
]}

Andjic, Mladen ^{[1
]}

Cvjeticanin, Mirjana Marjanovic ^{[1
,2
]}

Aksam, Slavica ^{[1
,2
]}

Bila, Jovan ^{[1
,2
]}

Tulic, Lidija ^{[1
,2
]}

Belovic, Dusica Kocijancic ^{[1
,2
]}

Plesinac, Vera ^{[1
]}

Plesinac, Jovana ^{[4
]}

机构：

[1] Univ Clin Ctr Serbia, Clin Gynecol & Obstet, Belgrade 11000, Serbia

[2] Univ Belgrade, Fac Med, Belgrade 11000, Serbia

[3] Univ Clin Ctr Serbia, Dept Neonatol, Clin Gynecol & Obstet, Belgrade 11000, Serbia

[4] Univ Clin Ctr Serbia, Belgrade 11000, Serbia

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 01期

关键词：

gestational diabetes mellitus; antenatal corticosteroids; glycemia; fetus; preterm birth; neonates; respiratory distress syndrome; LATE PRETERM; RISK-FACTORS; PREGNANCIES; WOMEN; GROWTH; BETAMETHASONE; HYPOGLYCEMIA; METABOLISM; SYSTEM; BIRTH;

D O I：

10.3390/jcm12010323

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: There, we review the pathogenesis of gestational diabetes mellitus (GDM), its influence on fetal physiology, and neonatal outcomes, as well as the usage of antenatal corticosteroid therapy (ACST) in pregnancies complicated by GDM. Methods: MEDLINE and PubMed search was performed for the years 1990-2022, using a combination of keywords on such topics. According to the aim of the investigation, appropriate articles were identified and included in this narrative review. Results: GDM is a multifactorial disease related to unwanted pregnancy course and outcomes. Although GDM has an influence on the fetal cardiovascular and nervous system, especially in preterm neonates, the usage of ACST in pregnancy must be considered taking into account maternal and fetal characteristics. Conclusions: GDM has no influence on neonatal outcomes after ACST introduction. The ACST usage must be personalized and considered according to its gestational age-specific effects on the developing fetus.

引用

页数：12

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