Effects of combined complement complement and CD14 inhibition on Escherichia coli-induced thromboinflammation in human whole blood in the presence and absence of antibiotics

被引:0
作者
Joakimsen, Ingrid Sofie [1 ,2 ]
Karlsen, Bard Ove [1 ,2 ]
Emblem, Ase Eeg [1 ,2 ]
Pettersen, Kristin [1 ,2 ]
Gronli, Renate Henriksen [1 ,2 ]
Mollnes, Tom Erik [1 ,2 ,3 ]
Brekke, Ole-Lars [1 ,2 ,4 ]
机构
[1] Nordland Hosp, Res Lab, Bodo, Norway
[2] Nordland Hosp, Dept Lab Med, Bodo, Norway
[3] Univ Oslo, Oslo Univ Hosp, Dept Immunol, Oslo, Norway
[4] UiT Arctic Univ Norway, Inst Clin Med, Tromso, Norway
关键词
D O I
10.1016/j.imbio.2023.152679
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
229
引用
收藏
页码:97 / 97
页数:1
相关论文
共 50 条
[41]   Combined inhibition of C5 and CD14 attenuates organ inflammation in porcine Escherichia coli sepsis [J].
Egge, K. H. ;
Thorgersen, E. B. ;
Lindstad, J. K. ;
Pharo, A. M. ;
Bongoni, A. K. ;
Rieben, R. ;
Barratt-Due, A. ;
Mollnes, T. E. .
MOLECULAR IMMUNOLOGY, 2013, 56 (03) :246-246
[42]   Differential role of C5a receptor and CD14 in E. coli-induced upregulation of granulocyte and monocyte CD11b (CR3) in human whole blood [J].
Brekke, OL ;
Fure, H ;
Christiansen, D ;
Fung, M ;
Mollnes, TE .
MOLECULAR IMMUNOLOGY, 2003, 40 (2-4) :180-181
[43]   Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis [J].
Barratt-Due, Andreas ;
Thorgersen, Ebbe B. ;
Egge, Kjetil ;
Pischke, Soren ;
Sokolov, Andrey ;
Hellerud, Bernt C. ;
Lindstad, Julie K. ;
Pharo, Anne ;
Bongoni, Anjan K. ;
Rieben, Robert ;
Nunn, Miles ;
Scott, Helge ;
Mollnes, Tom E. .
JOURNAL OF IMMUNOLOGY, 2013, 191 (02) :819-827
[44]   Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14 [J].
Egge, Kjetil H. ;
Thorgersen, Ebbe B. ;
Pischke, Soren E. ;
Lindstad, Julie K. ;
Pharo, Anne ;
Bongoni, Anjan K. ;
Rieben, Robert ;
Nunn, Miles A. ;
Barratt-Due, Andreas ;
Mollnes, Tom E. .
IMMUNOBIOLOGY, 2015, 220 (08) :999-1005
[45]   CD14 blockade down-regulates kidney C3 gene expression in Escherichia coli-induced sepsis in vivo in pigs [J].
Pischke, S. E. ;
Pharo, A. ;
Lindstad, J. K. ;
Hellerud, B. C. ;
Olafsrud, S. Mjelstad ;
Tonnessen, T. I. ;
Thorgersen, E. Billmann ;
Mollnes, T. E. .
MOLECULAR IMMUNOLOGY, 2011, 48 (14) :1693-1693
[46]   Complement (C5)-inhibition attenuates heme-induced inflammation in human whole blood [J].
Thomas, Anub Mathew ;
Gerogianni, Alexandra ;
Barratt-Due, Andreas ;
McAdam, Martin B. ;
Mollnes, Tom Eirik ;
Nilsson, Per H. .
MOLECULAR IMMUNOLOGY, 2018, 102 :220-220
[47]   Key role of complement receptor 1 in the initial binding of Escherichia coli and Neisseria meningitidis to erythrocytes in human whole blood [J].
Brekke, Ole-Lars ;
Christiansen, Dorte ;
Hellerud, Bernt Christian ;
Fure, Hilde ;
Bergseth, Grethe ;
Leslie, Graham ;
Lambris, John ;
Mollnes, Tom Eirik .
MOLECULAR IMMUNOLOGY, 2008, 45 (16) :4149-4149
[48]   Key role of complement receptor 1 in the initial binding of Escherichia coli and Neisseria meningitidis to erythrocytes in human whole blood [J].
Brekke, Ole-Lars ;
Hellerud, Bernt Christian ;
Christiansen, Dorte ;
Fure, Hilde ;
Bergseth, Grethe ;
Leslie, Graham ;
Lambris, John ;
Mollnes, Tom Eirik .
MOLECULAR IMMUNOLOGY, 2009, 46 (14) :2824-2824
[49]   HYPOXIA FOLLOWED BY WHOLE BLOOD REOXYGENATION INDUCED ENDOTHELIAL CELL ACTIVATION IN A COMPLEMENT C5 AND TOLL-LIKE RECEPTOR CD14 DEPENDENT MANNER [J].
Sokolova, Marina ;
Ekholt, Karin ;
Mollnes, Tom Eirik ;
Pischke, Soren Erik .
MOLECULAR IMMUNOLOGY, 2019, 114 :479-479
[50]   Combined C5aR1 and CD14 inhibition significantly reduced cytokine release induced by both viable and heat inactivated bacteria in human whole blood [J].
Christiansen, Dorte ;
Skjeflo, Espen Waage ;
Landsem, Anne ;
Fure, Hilde ;
Ludviksen, Judith K. ;
Stenvik, Jurgen ;
Woodruff, Trent ;
Espevik, Terje ;
Mollnes, Tom Eirik .
MOLECULAR IMMUNOLOGY, 2017, 89 :169-170