Photodriven Radical Perfluoroalkylation-Thiolation of Unactivated Alkenes Enabled by Electron Donor-Acceptor Complex

被引：9
作者：
Liu, Lixin [1 ]
Wang, Qian [1 ]
Li, Yuanhua [1 ]
Liu, Min [1 ]
Liu, Bifu [1 ]
Li, Qiang [2 ]
Feng, Kejun [1 ]
机构：
[1] Huizhou Univ, Sch Chem & Mat Engn, Huizhou 516007, Peoples R China
[2] Liaocheng Univ, Sch Chem & Chem Engn, Shandong Prov Key Lab Chem Energy Storage & Novel, Liaocheng 252000, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 11期
基金：
中国国家自然科学基金;
关键词：
PHOTOREDOX; DIFUNCTIONALIZATION; TRIFLUOROMETHYLATION; REAGENTS; OXYGEN;
D O I：
10.1021/acs.orglett.4c00462
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A clean and direct three-component radical 1,2-difunctionalization of various alkenes with perfluoroalkyl iodides and thiosulfonates enabled by the electron donor-acceptor complex has been developed under light illumination at room temperature. The approach offers a convenient and environmentally friendly route for the simultaneous incorporation of Csp(3)-Rf and Csp(3)-S bonds, affording valuable polyfunctionalized alkane derivatives containing fluorine and sulfur in satisfactory yields. Consequently, this methodology holds significant value and practicality in the field of organic synthesis.
引用
收藏
页码：2271 / 2275
页数：5
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