Association between symptoms of severe periodontitis and post-bronchodilator lung function: results from the China pulmonary health study

被引:0
作者
Liu, Zhiqiang [1 ]
Zhou, Xuan [1 ]
Liang, Lirong [2 ,3 ]
Han, Xiaozhe [4 ]
Yang, Ting [5 ,6 ,7 ,8 ]
Huang, Kewu [3 ,9 ]
Lin, Yingxiang [3 ,9 ]
Wang, Zuomin [1 ]
Wang, Chen [5 ,6 ,7 ,8 ,10 ]
机构
[1] Capital Med Univ, Beijing Chao Yang Hosp, Dept Stomatol, 8 Gongti South Rd, Beijing 100020, Peoples R China
[2] Capital Med Univ, Beijing Chao Yang Hosp, Dept Clin Epidemiol, Beijing, Peoples R China
[3] Beijing Inst Resp Med, Beijing, Peoples R China
[4] Nova Southeastern Univ, Dept Oral Sci & Translat Res, Coll Dent Med, Ft Lauderdale, FL USA
[5] China Japan Friendship Hosp, Ctr Resp Med, Dept Pulm & Crit Care Med, 2 Yinghuayuan Dongjie, Beijing 100029, Peoples R China
[6] Natl Clin Res Ctr Resp Dis, Beijing, Peoples R China
[7] Peking Union Med Coll, Inst Resp Med, Beijing, Peoples R China
[8] Capital Med Univ, Dept Resp Med, Beijing, Peoples R China
[9] Beijing Chao Yang Hosp, Dept Pulm & Crit Care Med, Beijing Key Lab Resp & Pulm Circulat Disorders, Beijing, Peoples R China
[10] WHO Collaborating Ctr Tobacco Cessat & Resp Dis Pr, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
Lung function; Periodontitis; COPD; Cross-sectional; Epidemiology; Risk factor; DISEASES;
D O I
10.1186/s12890-023-02485-6
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
BackgroundThe association between periodontitis and post-bronchodilator lung function is unclear. We aimed to determine the associations between symptoms of severe periodontitis (SSP) and post-bronchodilator lung function in the Chinese population.MethodsA cross-sectional study (China Pulmonary Health study) was conducted from 2012 to 2015 in a large Chinese nationally representative sample of 49,202 participants aged 20-89 years. Data on demographic characteristics and periodontal symptoms of participants were collected by questionnaire. Participants who had at least one of the two severe symptoms (tooth mobility and natural tooth loss) in the past year were defined to have SSP, which was set as one variable for analyses. Post-bronchodilator lung function data including forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were collected by spirometry.ResultsThe values of post-FEV1, post-FVC and post-FEV1/FVC of the participants with SSP were all significantly lower than the participants without SSP (all p < 0.001). SSP were significantly associated with post-FEV1/FVC < 0.7 (p < 0.001). In the multiple regression analyses, SSP were still negatively associated with post-FEV1(b = -0.04, 95%CI (-0.05 -0.03), p < 0.001), post-FEV1/FVC (b = -0.45, 95%CI (-0.63, -0.28), p < 0.001) and significantly associated with post-FEV1/FVC < 0.7 (OR = 1.08, 95%CI 1.01-1.16, p = 0.03) after full adjustment for potential confounders.ConclusionsOur data suggest that SSP were negatively associated with post-bronchodilator lung function in the Chinese population. Longitudinal cohort studies are needed to confirm these associations in the future.
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页数:9
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