A quantitative analysis of surgical smoke-derived particulate matter and formaldehyde exposure during spine surgery: a possible occupational hazard

被引:0
作者
Choi, Seung Jin [1 ]
Seo, Dongmin [1 ]
Ham, Chang Hwa [1 ]
Kim, Joo Han [1 ]
Kwon, Woo-Keun [1 ,2 ]
机构
[1] Korea Univ, Guro Hosp, Coll Med, Dept Neurosurg, Seoul, South Korea
[2] Korea Univ, Guro Hosp, Coll Med, Seoul, South Korea
基金
新加坡国家研究基金会;
关键词
surgical smoke; electrocautery; particulate matter; formaldehyde; hazard; ULTRAFINE PARTICLES; HEALTH; ELECTROCAUTERY; THEATER; CANCER; RISKS;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: We hypothesized that OR airborne PM was different in quantity and mutagenic potential than office air and cigarette smoke. Summary of background data: Exposure to surgical smoke has been equated to cigarette smoking and thought to be hazardous to health care workers despite limited data. Methods: PM was measured during 15 operations in ORs with 24.8 +/- 2.0 air changes/h, and in controls (cigarettes, office air with 1.9-2.9 air changes/h). Mutagenic potential was assessed by gamma Histone 2A family member X staining of DNA damage in small airway epithelial cells co-cultured with PM. Results: Average PM concentration during surgery was 0.002 +/- 0.002 mg/m3 with maximum values at 1.08 +/- 1.30 mg/m3. Greater PM correlated with more diathermy (rho = 0.69, P = 0.006). Values were most often near zero, resulting in OR average values similar to office air (0.002 +/- 0.001 mg/m3) (P = 0.32). Cigarette smoke average PM concentration was significantly higher, 4.8 +/- 5.6 mg/m3 (P < 0.001). PM collected from 14 days of OR air caused DNA damage to 1.6% +/- 2.7% of cultured cells, significantly less than that from office air (27.7% +/- 11.7%, P = 0.02), and cigarette smoke (61.3% +/- 14.3%, P < 0.001). Conclusions: The air we breathe during surgery has negligible quantities of PM and mutagenic potential, likely due to low frequency of diathermy use coupled with high airflow. This suggests that exposure to surgical smoke is associated with minimal occupational risk.
引用
收藏
页码:395 / 402
页数:8
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