Changes in Radiation Therapy: New Ultrahypofractionated Radiation, Repeat Breast Conservation Therapy in the Management of Breast Recurrence with Re-irradiation, Proton Therapy

被引:0
作者
Lupinacci, Kristin M. [1 ]
Sabih, Quratulain [1 ]
Mulherkar, Ria [2 ]
Vargo, John A. [2 ]
Diego, Emilia J. [1 ]
机构
[1] Univ Pittsburgh, Dept Surg, Div Breast Surg, Sch Med, 300 Halket St,Suite 2601, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Sch Med, Dept Radiat Oncol, Pittsburgh, PA USA
关键词
Breast conservation therapy; Breast cancer recurrence; Re-irradiation; Ultrahypofractionated radiation; Proton therapy; ONCOLOGY CONSENSUS GUIDELINE; COMPARING TOTAL MASTECTOMY; 20-YEAR FOLLOW-UP; CONSERVING SURGERY; RADICAL-MASTECTOMY; ALTERNATIVE TREATMENTS; AMERICAN SOCIETY; RANDOMIZED-TRIAL; MARGIN STATUS; IN-SITU;
D O I
10.1007/s12609-024-00544-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose of ReviewManagement of breast cancer is multidisciplinary, balancing local and systemic control between treatment modalities. Surgical, radiation, and medical therapies are combined to give the best prognosis. The goal of this review is to examine the advancements in radiotherapy in the treatment of breast cancer.Recent FindingsPublished data supports the shortening of radiation schedules through ultrahypofractionation and utilizing new energy sources through proton beam radiation. Emerging techniques have minimized radiation dosage to organs at risk and skin when compared to traditional radiation sources and plans. Traditionally an ipsilateral breast tumor recurrence after breast conservation therapy necessitated mastectomy. Re-irradiation is now an alternative option with comparable outcomes.SummaryAdvances in radiotherapy have contributed to more patients choosing breast-conserving surgery over mastectomy. This has prompted the investigation of alternative technologies and techniques to decrease toxicities, while maintaining oncologic efficacy
引用
收藏
页码:204 / 211
页数:8
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