DNA DAMAGE SENSING KINASES ATR AND ATM-DEPENDENT PHOSPHORYLATION OF RRM2 PROMOTES PROTEIN STABILIZATION AND CHEMO-ADAPTATION

被引：0
|
作者：
McManus, Graysen [1 ]
Perrault, Ella [2 ]
Park, Cheol [3 ]
Ventrapragada, Divya [3 ]
Budhiraja, Shreya [3 ]
Buechler, Killian [3 ]
Stepniak, Amelia [3 ]
Mishra, Snehasis [3 ]
Miska, Jason [3 ]
Ahmed, Atique [1 ]
机构：
[1] Northwestern Univ, Feinberg Sch Med, Dept Neurol Surg, Chicago, IL 60611 USA
[2] Harvard Univ, Chicago, IL USA
[3] Northwestern Univ, Chicago, IL 60611 USA
来源：
NEURO-ONCOLOGY | 2023年 / 25卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
DDDR-28
引用
收藏
页数：2
相关论文
共 16 条
  • [1] ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response
    Guo, Yingying
    Feng, Wanjuan
    Sy, Shirley M. H.
    Huen, Michael S. Y.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (46) : 27545 - 27556
  • [2] ATM-Dependent Phosphorylation of MEF2D Promotes Neuronal Survival after DNA Damage
    Chan, Shing Fai
    Sances, Sam
    Brill, Laurence M.
    Okamoto, Shu-ichi
    Zaidi, Rameez
    McKercher, Scott R.
    Akhtar, Mohd W.
    Nakanishi, Nobuki
    Lipton, Stuart A.
    JOURNAL OF NEUROSCIENCE, 2014, 34 (13): : 4640 - 4653
  • [3] ATM-dependent phosphorylation of ATF2 is required for the DNA damage response
    Bhoumik, A
    Takahashi, S
    Breitweiser, W
    Shiloh, Y
    Jones, N
    Ronai, Z
    MOLECULAR CELL, 2005, 18 (05) : 577 - 587
  • [4] ATM-dependent stabilization of human PMS1 protein in response to DNA damage.
    Lin, WC
    Luo, YH
    BLOOD, 2002, 100 (11) : 304A - 304A
  • [5] Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage
    Pereg, Y
    Shkedy, D
    de Graaf, P
    Meulmeester, E
    Edelson-Averbukh, M
    Salek, M
    Biton, S
    Teunisse, AFAS
    Lehmann, WD
    Jochemsen, AG
    Shiloh, Y
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (14) : 5056 - 5061
  • [6] DNA Damage Regulates the Functions of the RNA Binding Protein Sam68 through ATM-Dependent Phosphorylation
    Stagni, Venturina
    Orecchia, Silvia
    Mignini, Luca
    Beji, Sara
    Antonioni, Ambra
    Caggiano, Cinzia
    Barila, Daniela
    Bielli, Pamela
    Sette, Claudio
    CANCERS, 2022, 14 (16)
  • [7] ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage
    Moumen, Abdeladim
    Magill, Christine
    Dry, Katherine L.
    Jackson, Stephen P.
    CELL CYCLE, 2013, 12 (04) : 698 - 704
  • [8] Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    Lin, WC
    Lin, FT
    Nevins, JR
    GENES & DEVELOPMENT, 2001, 15 (14) : 1833 - 1844
  • [9] The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response
    Karlseder, J
    Hoke, K
    Mirzoeva, OK
    Bakkenist, C
    Kastan, MB
    Petrini, JHJ
    de Lange, T
    PLOS BIOLOGY, 2004, 2 (08): : 1150 - 1156
  • [10] ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
    Maya, R
    Balass, M
    Kim, ST
    Shkedy, D
    Leal, JFM
    Shifman, O
    Moas, M
    Buschmann, T
    Ronai, Z
    Shiloh, Y
    Kastan, MB
    Katzir, E
    Oren, M
    GENES & DEVELOPMENT, 2001, 15 (09) : 1067 - 1077
12