STRUCTURAL CONSTRAINED VIRTUAL HISTOLOGY STAINING FOR HUMAN CORONARY IMAGING USING DEEP LEARNING

被引:2
作者
Li, Xueshen [1 ]
Liu, Hongshan [1 ]
Song, Xiaoyu [3 ]
Brott, Brigitta C. [2 ]
Litovsky, Silvio H. [2 ]
Gan, Yu [1 ]
机构
[1] Stevens Insitute Technol, Dept Biomed Engn, Hoboken, NJ 07030 USA
[2] Univ Alabama Birmingham, Sch Med, Birmingham, AL USA
[3] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
来源
2023 IEEE 20TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING, ISBI | 2023年
基金
美国国家科学基金会;
关键词
Virtual histology; Coronary artery disease; Optical coherence tomography; Deep learning; OPTICAL COHERENCE TOMOGRAPHY;
D O I
10.1109/ISBI53787.2023.10230480
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using Optical Coherence Tomography (OCT) images to enable real-time histological visualization. We develop a deep learning network, namely Coronary-GAN, to transfer coronary OCT images to virtual histology images. With a special consideration on the structural constraints in coronary OCT images, our method achieves better image generation performance than the conventional GAN-based method. The experimental results indicate that Coronary-GAN generates virtual histology images that are similar to real histology images, revealing the human coronary layers.
引用
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页数:5
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