Impact of COVID-19 infection during pregnancy on maternal and fetal outcomes

被引:1
作者
Anter, Mohamed Elsibai [1 ]
Abd El-Aal, Nasser Kamal [1 ]
Rezk, Mohamed Abd Allah [1 ]
Moawad, Hussein Fahmy [1 ,2 ]
Abudakika, Ahmed Tharwat [1 ]
机构
[1] Menoufia Univ, Fac Med, Obstet & Gynecol Dept, Menoufia, Egypt
[2] Al Bagour Gen Hosp, Obstet & Gynecol, Menoufia, Egypt
关键词
COVID-19; Hospitals; Infant; Quarantine; Pregnancy outcome; Prenatal care; Women;
D O I
10.1097/RD9.0000000000000044
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives:The objective of this study is to assess the impact of coronavirus disease 2019 (COVID-19) infection during pregnancy on maternal and fetal outcome in relation to gestational age. Methods:This retrospective study was conducted between May 2020 and July 2021. Sixty-five women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and hospitalized at a quarantine hospital were included. Thirty-four women received prenatal care at the hospital until delivery, while 31 dropped out from the study due to COVID-19 recovery and discharge before delivery. Results:COVID-19 was found in 83% of the pregnant women after 20 weeks of pregnancy. The most common symptoms were cough and fever. Medical complications included severe pneumonia and thrombosis. The maternal mortality rate was 9.2%. Premature rupture of membranes and severe hypertension during labor affected nearly 9% of the pregnant women who completed prenatal care until delivery at the hospital. Preterm labor occurred at a rate of 38.2%. There were seven (20.8%) stillbirths and two cases of infant mortality. Conclusion:Hospitalized pregnant women who have coronavirus infection, lymphopenia, and a high C-reactive protein level were at a higher risk of developing severe illness, which can lead to maternal and neonatal complications.
引用
收藏
页码:108 / 114
页数:7
相关论文
共 20 条
[1]   Clinical Presentation of Coronavirus Disease 2019 (COVID-19) in Pregnant and Recently Pregnant People [J].
Afshar, Yalda ;
Gaw, Stephanie L. ;
Flaherman, Valerie J. ;
Chambers, Brittany D. ;
Krakow, Deborah ;
Berghella, Vincenzo ;
Shamshirsaz, Alireza A. ;
Boatin, Adeline A. ;
Aldrovandi, Grace ;
Greiner, Andrea ;
Riley, Laura ;
Boscardin, W. John ;
Jamieson, Denise J. ;
Jacoby, Vanessa L. .
OBSTETRICS AND GYNECOLOGY, 2020, 136 (06) :1117-1125
[2]   Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis [J].
Allotey, John ;
Stallings, Elena ;
Bonet, Mercedes ;
Yap, Magnus ;
Chatterjee, Shaunak ;
Kew, Tania ;
Debenham, Luke ;
Llavall, Anna Clave ;
Dixit, Anushka ;
Zhou, Dengyi ;
Balaji, Rishab ;
Lee, Siang Ing ;
Qiu, Xiu ;
Yuan, Mingyang ;
Coomar, Dyuti ;
van Wely, Madelon ;
van Leeuwen, Elizabeth ;
Kostova, Elena ;
Kunst, Heinke ;
Khalil, Asma ;
Tiberi, Simon ;
Brizuela, Vanessa ;
Broutet, Nathalie ;
Kara, Edna ;
Kim, Caron Rahn ;
Thorson, Anna ;
Oladapo, Olufemi T. ;
Mofenson, Lynne ;
Zamora, Javier ;
Thangaratinam, Shakila .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 370
[3]   Maternal and perinatal characteristics and outcomes of pregnancies complicated with COVID-19 in Kuwait [J].
Ayed, Amal ;
Embaireeg, Alia ;
Benawadh, Asmaa ;
Al-Fouzan, Wadha ;
Hammoud, Majdeda ;
Al-Hathal, Monif ;
Alzaydai, Abeer ;
Ahmad, Ashraf ;
Ayed, Mariam .
BMC PREGNANCY AND CHILDBIRTH, 2020, 20 (01)
[4]   COVID-19 outcomes among pregnant and nonpregnant women at reproductive age in Egypt [J].
BahaaEldin, Hala ;
Sood, Hanaa Abu El ;
Samy, Sahar ;
Khader, Yousef ;
AbdelFatah, Mohamad ;
Hassany, Mohamed ;
Afifi, Salma ;
Eid, Alaa .
JOURNAL OF PUBLIC HEALTH, 2021, 43 :12-18
[5]   Immune Response to COVID-19 During Pregnancy [J].
Chen, Ge ;
Liao, Qiuyue ;
Ai, Jihui ;
Yang, Bin ;
Bai, Hualin ;
Chen, Jing ;
Liu, Fengyuan ;
Cao, Yang ;
Liu, Haiyi ;
Li, Kezhen .
FRONTIERS IN IMMUNOLOGY, 2021, 12
[6]  
Daru J, 2021, THROMBOSIS UPDATE, V5
[7]   COVID-19 in pregnancy-characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries [J].
Engjom, Hilde ;
Aabakke, Anna J. M. ;
Klungsoyr, Kari ;
Svanvik, Teresia ;
Ayras, Outi ;
Jonasdottir, Eva ;
Thurn, Lars ;
Jones, Elin ;
Pettersson, Karin ;
Nyflot, Lill T. ;
Al-Zirqi, Iqbal ;
Vangen, Siri ;
Juliusson, Petur B. ;
Kallen, Karin ;
Gissler, Mika ;
Krebs, Lone .
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2021, 100 (09) :1611-1619
[8]   The Differences in Clinical Presentation, Management, and Prognosis of Laboratory-Confirmed COVID-19 between Pregnant and Non-Pregnant Women: A Systematic Review and Meta-Analysis [J].
Khan, Durray Shahwar A. ;
Pirzada, Areeba N. ;
Ali, Anna ;
Salam, Rehana A. ;
Das, Jai K. ;
Lassi, Zohra S. .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (11)
[9]   Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study [J].
Knight, Marian ;
Bunch, Kathryn ;
Vousden, Nicola ;
Morris, Edward ;
Simpson, Nigel ;
Gale, Chris ;
O'Brien, Patrick ;
Quigley, Maria ;
Brocklehurst, Peter ;
Kurinczuk, Jennifer J. .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 369
[10]   SARS-CoV-2in the context of past coronaviruses epidemics: Consideration for prenatal care [J].
Lambelet, Valentine ;
Vouga, Manon ;
Pomar, Leo ;
Favre, Guillaume ;
Gerbier, Eva ;
Panchaud, Alice ;
Baud, David .
PRENATAL DIAGNOSIS, 2020, 40 (13) :1641-1654