Single-Cell profiling reveals aggressive tumor subcluster and compromised immune state in multiple myeloma

被引:0
|
作者
Sun, Hao [1 ,2 ]
Gong, Lixin [1 ,2 ]
Fang, Teng [1 ,2 ]
Yu, Zhen [1 ,2 ]
Liu, Lanting [1 ,2 ]
Wang, Tingyu [1 ,2 ]
An, Gang [1 ,2 ]
Qiu, Lugui [1 ,2 ]
Hao, Mu [1 ,2 ]
机构
[1] Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol,Haihe Lab Cell Ecosyst, Tianjin 300020, Peoples R China
[2] Chinese Acad Med Sci & Peking Union Med Coll, Blood Dis Hosp, Tianjin 300020, Peoples R China
来源
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P-414
引用
收藏
页码:S269 / S269
页数:1
相关论文
共 50 条
  • [31] Single-cell profiling of multiple myeloma reveals molecular response to FGFR3 inhibitor despite clinical progression
    Croucher, Danielle C.
    Devasia, Anup Joseph
    Abelman, Dor D.
    Mahdipour-Shirayeh, Ali
    Li, Zhihua
    Erdmann, Natalie
    Tiedemann, Rodger
    Pugh, Trevor J.
    Trudel, Suzanne
    COLD SPRING HARBOR MOLECULAR CASE STUDIES, 2023, 9 (02):
  • [32] Single-cell sequencing reveals the mechanisms of multiple myeloma progression: clarity or confusion?
    Xiang, Yunhui
    Sun, Guokang
    Tian, Lvbo
    Xiang, Pinpin
    Xie, Chunbao
    ANNALS OF HEMATOLOGY, 2025, 104 (02) : 895 - 912
  • [33] Single cell transcriptomics reveals the impact of tumor cell interactions with the bone marrow immune microenvironment in the progression of multiple myeloma
    Sudha, Parvathi
    Abu Zaid, Mohammad
    Johnson, Travis
    Chopra, Vivek
    Dos Santos, Cedric
    Nixon, Michael
    Zafar, Faiza
    Hamidi, Habib
    Suvannasankha, Attaya
    Farag, Sherif
    Lee, Kelvin
    Abonour, Rafat
    Walker, Brian
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S16 - S17
  • [34] Single-cell profiling reveals dynamic epithelial and immune cell interactions in the progression of lung adenocarcinoma
    Chen, Hong
    Zhu, Bo
    Fujimoto, Junya
    Tian, Yanhua
    Li, Jian-Rong
    Li, Chenyang
    Chen, Pingjun
    Reuben, Alexandre
    Nilsson, Monique
    Le, Xiuning
    Poteete, Alissa
    Hubert, Shawna M.
    Gibbons, Don L.
    Wistuba, Ignacio I.
    Wu, Jia
    Cheng, Chao
    Heymach, John V.
    Zhang, Jianjun
    CANCER RESEARCH, 2024, 84 (06)
  • [35] Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
    Schinke, Carolina
    Poos, Alexandra M.
    Bauer, Michael
    John, Lukas
    Johnson, Sarah
    Deshpande, Shayu
    Carrillo, Luis
    Alapat, Daisy
    Rasche, Leo
    Thanendrarajan, Sharmilan
    Zangari, Maurizio
    Al Hadidi, Samer
    van Rhee, Frits
    Davies, Faith
    Raab, Marc S.
    Morgan, Gareth
    Weinhold, Niels
    BLOOD ADVANCES, 2022, 6 (22) : 5873 - 5883
  • [36] Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation
    Kummerlowe, Conner
    Mwakamui, Simutanyi
    Hughes, Travis K.
    Mulugeta, Nolawit
    Mudenda, Victor
    Besa, Ellen
    Zyambo, Kanekwa
    Shay, Jessica E. S.
    Fleming, Ira
    Vukovic, Marko
    Doran, Ben A.
    Aicher, Toby P.
    Wadsworth, Marc H., II
    Bramante, Juliet Tongue
    Uchida, Amiko M.
    Fardoos, Rabiah
    Asowata, Osaretin E.
    Herbert, Nicholas
    Yilmaz, Omer H.
    Kloverpris, Henrik N.
    Garber, John J.
    Ordovas-Montanes, Jose
    Gartner, Zev J.
    Wallach, Thomas
    Shalek, Alex K.
    Kelly, Paul
    SCIENCE TRANSLATIONAL MEDICINE, 2022, 14 (660)
  • [37] Single-cell profiling reveals the metastasis-associated immune signature of hepatocellular carcinoma
    Zhong, Deyuan
    Shi, Ying
    Ma, Wenzhe
    Liang, Yuxin
    Liu, Hanjie
    Qin, Yingying
    Zhang, Lu
    Yang, Qinyan
    Huang, Xiaolun
    Lu, Yuanjun
    Shang, Jin
    IMMUNITY INFLAMMATION AND DISEASE, 2024, 12 (05)
  • [38] Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancer
    Yanhua Tian
    Qingqing Li
    Zhenlin Yang
    Shu Zhang
    Jiachen Xu
    Zhijie Wang
    Hua Bai
    Jianchun Duan
    Bo Zheng
    Wen Li
    Yueli Cui
    Xin Wang
    Rui Wan
    Kailun Fei
    Jia Zhong
    Shugeng Gao
    Jie He
    Carl M. Gay
    Jianjun Zhang
    Jie Wang
    Fuchou Tang
    Signal Transduction and Targeted Therapy, 7
  • [39] Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancer
    Tian, Yanhua
    Li, Qingqing
    Yang, Zhenlin
    Zhang, Shu
    Xu, Jiachen
    Wang, Zhijie
    Bai, Hua
    Duan, Jianchun
    Zheng, Bo
    Li, Wen
    Cui, Yueli
    Wang, Xin
    Wan, Rui
    Fei, Kailun
    Zhong, Jia
    Gao, Shugeng
    He, Jie
    Gay, Carl M.
    Zhang, Jianjun
    Wang, Jie
    Tang, Fuchou
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 7 (01)
  • [40] Single-Cell Pathway Enrichment and Regulatory Profiling of Multiple Myeloma across Disease Stages
    Wang, Tianjiao
    Sun, Hua
    Zhou, Daniel Cui
    Liu, Ruiyang
    Yao, Lijun
    Fiala, Mark A.
    Kohnen, Daniel R.
    O'Neal, Julie
    Rettig, Michael P.
    Fowles, Jared S.
    Oh, Stephen T.
    Jayasinghe, Reyka G.
    Vij, Ravi
    DiPersio, John F.
    Ding, Li
    BLOOD, 2019, 134