Recent Advances in Engineering Bioinks for 3D Bioprinting

被引：1

作者：

Wang, Haonan ^{[1
]}

Bi, Shihao ^{[2
]}

Shi, Bingbing ^{[3
]}

Ma, Junchi ^{[4
]}

Lv, Xiangwei ^{[3
]}

Qiu, Jianfeng ^{[4
,5
]}

Wei, Yunyun ^{[1
,4
]}

机构：

[1] Shandong First Med Univ, Sch Radiol, Affiliated Hosp 2, Tai An 271000, Peoples R China

[2] Shandong First Med Univ & Shandong Acad Med Sci, Neck Shoulder & Lumbocrural Pain Hosp First Med Un, Jinan 250000, Shandong, Peoples R China

[3] Shandong First Med Univ & Shandong Acad Med Sci, Dept Clin Med, Tai An, Peoples R China

[4] Shandong First Med Univ & Shandong Acad Med Sci, Sch Radiol, Tai An, Peoples R China

[5] Shandong First Med Univ & Shandong Acad Med Sci, Sci & Technol Innovat Ctr, Jinan, Peoples R China

来源：

ADVANCED ENGINEERING MATERIALS | 2023年 / 25卷 / 19期

关键词：

3D bioprinting; bioink; biomaterial; biomolecules; tissue engineering; STEM CELL-LADEN; HYALURONIC-ACID; GELATIN HYDROGELS; IN-VITRO; TISSUE CONSTRUCTS; 3D-PRINTED SCAFFOLDS; PRINTING PROCESS; ALGINATE; AGAROSE; BIOMATERIALS;

D O I：

10.1002/adem.202300648

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The 3D bioprinting can controllably deposit bioink containing cells and fabricate complex bionic tissue structures in a fast and scalable way, which is expected to completely change the scenario of clinical organ transplantation. Bioprinting holds broad application prospect in tissue engineering, life sciences, and clinical medicine. In the process of 3D bioprinting, bioink, as the carrier of cells and bioactive substances, influences cell activity and accuracy of organ structure after printing. To better understand and design bioink, in this review, the concept, development, and basic composition of bioink are introduced, while focusing on the advantages and disadvantages of various biomaterials, and the use of common cells and biomolecules that constitute bioink. In addition, the properties and applications of various stimuli-responsive smart materials for 4D bioprinting are mentioned. The challenges and development trends of bioink are also summarized.

引用

页数：17

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