EVALUATION OF THE ANTI-INFLAMMATORY ROLE OF A NATURAL PRODUCT WITH ARNICA MONTANA EXTRACT AND BOSWELLIA SERRATA RESIN

Arnica montana and Boswellia serrata are plants with very important properties, among which the strong anti-inflammatory activity stands out. This study aimed to evaluate the anti-inflammatory activity of a mixture of the two compounds (Arnica montana and Boswellia serrata) in an experiment on rats (carrageenan-induced oedema, at the level of the paw) by comparing the effect obtained with a gel with extract of Arnica. Rats were treated with Arnica gel and with a mixture of Arnica and Boswellia serrata extract and a significant reduction in carrageenan-induced paw oedema was observed (p < 0.05). For the Arnica gel, an inhibition of edema appeared 5 hours after the carrageenan injection. The inhibitory effect of the natural mixture with Arnica montana and Boswellia serrata extract began 3 hours after the carrageenan injection, demonstrating that both compounds produce antiinflammatory effects in the second phase of oedema, indicating the inhibition of prostaglandin synthesis. Both the reference product (Arnica gel) and the tested mixture showed anti-inflammatory action, but following the measurements, it could be concluded that the mixture was more effective in reducing oedema.