Which Factors Influence Healthy Aging? A Lesson from the Longevity Village of Bama in China

被引：8
作者：
Zhang, Wei [1 ,2 ,3 ,6 ]
Huang, Qingyun [1 ,2 ,3 ,6 ]
Kang, Yongxin [1 ,2 ,4 ,5 ,6 ]
Li, Hao [1 ,2 ,4 ,5 ,6 ]
Tan, Guohe [1 ,2 ,3 ,4 ,5 ,6 ,7 ]
机构：
[1] Guangxi Med Univ, Inst Neurosci, Sch Basic Med Sci, Dept Human Anat, Nanning, Guangxi, Peoples R China
[2] Guangxi Med Univ, Sch Basic Med Sci, Guangxi Key Lab Brain Sci, Guangxi Hlth Commiss Key Lab Basic Res Brain Funct, Nanning, Guangxi, Peoples R China
[3] Chinese Minist Educ, Key Lab Longev & Aging related Dis, Nanning, Guangxi, Peoples R China
[4] Collaborat Innovat Ctr Regenerat Med & Med BioReso, Guangxi Key Lab Regenerat Med, Nanning, Guangxi, Peoples R China
[5] Applicat Coconstructed Prov & Minist, Guangxi Key Lab Regenerat Med, Nanning, Guangxi, Peoples R China
[6] China ASEAN Res Ctr Innovat & Dev Brain Sci, Nanning, Guangxi, Peoples R China
[7] Guangxi Med Univ, Inst Neurosci, Sch Basic Med Sci, Nanning, Guangxi, Peoples R China
来源：
AGING AND DISEASE | 2023年 / 14卷 / 03期
基金：
中国国家自然科学基金;
关键词：
longevity; bama; healthy aging; gene polymorphism; environment; TELOMERE LENGTH DYNAMICS; SONCHUS-OLERACEUS L; DNA METHYLATION; LIFE-SPAN; CARDIOVASCULAR-DISEASE; MEDITERRANEAN DIET; METABOLIC SYNDROME; SEX-DIFFERENCES; TRACE-ELEMENTS; LIPID LEVELS;
D O I：
10.14336/AD.2022.1108
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
A growing aging population is associated with increasing incidences of aging-related diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is urgently needed. Longevity is an important phenomenon in healthy aging. The present review summarizes the characteristics of longevity in the elderly population in Bama, China, where the proportion of centenarians is 5.7-fold greater than the international standard. We examined the impact of genetic and env ironmental factors on longevity from multiple perspectives. We proposed that the phenomenon of longevity in this region is of high value for future investigations in healthy aging and aging-related disease and may provide guidance for fostering the establishment and maintenance of a healthy aging society.
引用
收藏
页码：825 / 839
页数：15
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