Monascin and ankaflavin-Biosynthesis from Monascus purpureus, production methods, pharmacological properties: A review

被引:31
作者
Adin, Syeda Nashvia [1 ]
Gupta, Isha [1 ]
Panda, Bibhu Prasad [1 ]
Mujeeb, Mohd [1 ]
机构
[1] Jamia Hamdard, Dept Pharmacognosy & Phytochem, Sch Pharmaceut Educ & Res, New Delhi 110062, India
关键词
fermentation; ankaflavin; monascin; Monascus pigments; Monascus purpureus; Monascus yellow pigments; SOLID-STATE FERMENTATION; HIGH-FAT DIET; PIGMENT PRODUCTION; PPAR-GAMMA; FUNGUS MONASCUS; MONACOLIN K; SECONDARY METABOLITES; ETHANOL FERMENTATION; CITRININ PRODUCTION; INSULIN-RESISTANCE;
D O I
10.1002/bab.2336
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Monascus purpureus copiously yields beneficial secondary metabolites , including Monascus pigments, which are broadly used as food additives, as a nitrite substitute in meat products, and as a colorant in the food industry. Monascus yellow pigments (monascin and ankaflavin) have shown potential antidiabetic, antibacterial, anti-inflammatory, antidepressant, antibiotic, anticancer, and antiobesity activities. Cosmetic and textile industries are other areas where it has established its potential as a dye. This paper reviews the production methods of Monascus yellow pigments, biosynthesis of Monascus pigments from M. purpureus, factors affecting yellow pigment production during fermentation, and the pharmacological properties of monascin and ankaflavin.
引用
收藏
页码:137 / 147
页数:11
相关论文
共 94 条
[1]   Enhancement of Monascus pigment production by the culture of Monascus sp J101 at low temperature [J].
Ahn, J ;
Jung, J ;
Hyung, W ;
Haam, S ;
Shin, C .
BIOTECHNOLOGY PROGRESS, 2006, 22 (01) :338-340
[2]   Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice) [J].
Akihisa, T ;
Tokuda, H ;
Ukiya, M ;
Kiyota, A ;
Yasukawa, K ;
Sakamoto, N ;
Kimura, Y ;
Suzuki, T ;
Takayasu, J ;
Nishino, H .
CHEMISTRY & BIODIVERSITY, 2005, 2 (10) :1305-1309
[3]   Optimization of medium for indole-3-acetic acid production using Pantoea agglomerans strain PVM [J].
Apine, O. A. ;
Jadhav, J. P. .
JOURNAL OF APPLIED MICROBIOLOGY, 2011, 110 (05) :1235-1244
[4]   Solid-state fermentation for the production of Monascus pigments from jackfruit seed [J].
Babitha, Sumathy ;
Soccol, Carlos R. ;
Pandey, Ashok .
BIORESOURCE TECHNOLOGY, 2007, 98 (08) :1554-1560
[5]  
Babitha S, 2006, FOOD TECHNOL BIOTECH, V44, P465
[6]   Ethanol fermentation technologies from sugar and starch feedstocks [J].
Bai, F. W. ;
Anderson, W. A. ;
Moo-Young, M. .
BIOTECHNOLOGY ADVANCES, 2008, 26 (01) :89-105
[7]  
Bangrak P, 2011, BRAZ J MICROBIOL, V42, P676, DOI [10.1590/S1517-83822011000200032, 10.1590/S1517-838220110002000032]
[8]   EFFECT OF DIFFERENT NITROGEN-SOURCES ON PIGMENT PRODUCTION AND SPORULATION OF MONASCUS SPECIES IN SUBMERGED, SHAKEN CULTURE [J].
CARELS, M ;
SHEPHERD, D .
CANADIAN JOURNAL OF MICROBIOLOGY, 1977, 23 (10) :1360-1372
[9]  
Carvalho JC, 2003, AGRO FOOD IND HI TEC, V14, P37
[10]  
Carvalho Julio C., 2007, Indian Journal of Biotechnology, V6, P194