Nonbacterial Thrombotic Endocarditis Caused by Early-stage Lung Cancer: An Autopsy Case Report

被引：1

作者：

Nagao, Tomoaki ^{[1
]}

Sakamoto, Atsushi ^{[1
]}

Fujihiro, Mayu ^{[2
]}

Kawakami, Rika ^{[3
]}

Suwa, Kenichiro ^{[1
]}

Hattori, Kazuya ^{[4
]}

Ohtani, Hayato ^{[1
]}

Saotome, Masao ^{[1
]}

Baba, Satoshi ^{[2
]}

V. Finn, Aloke ^{[3
]}

Maekawa, Yuichiro ^{[1
]}

机构：

[1] Hamamatsu Univ Sch Med, Div Cardiol, Internal Med 3, Hamamatsu, Japan

[2] Hamamatsu Univ Sch Med, Dept Diagnost Pathol, Hamamatsu, Japan

[3] CVPath Inst, Gaithersburg, MD USA

[4] Shizuoka Saiseikai Gen Hosp, Dept Diagnost Pathol, Shizuoka, Japan

来源：

INTERNAL MEDICINE | 2024年 / 63卷 / 01期

关键词：

nonbacterial thrombotic endocarditis; lung cancer; clinical early stage; autopsy;

D O I：

10.2169/internalmedicine.2004-23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nonbacterial thrombotic endocarditis (NBTE) is a manifestation of prothrombotic status observed in patients with malignancy. Most cases are discovered only in the advanced stages. However, cancer in early stages may also induce NBTE development. We herein report an 87-year-old man with NBTE with multiple thromboembolization coexisting with lung cancer in early clinical stage. Autopsy findings revealed platelet and fibrin-rich vegetations in both the tricuspid and mitral valves without evidence of bacterial infection. NBTE should be considered in cases with occult thromboembolization. Not only the presence of typical vegetation but irregular leaflet thickening should be monitored with careful echocardiographic examinations.

引用

页码：87 / 92

页数：6

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