direct oral anticoagulant (doac);
doac;
anticoagulation;
endoscopy;
gastrointestinal bleed;
UPDATE;
D O I:
10.7759/cureus.37591
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
The location of gastrointestinal (GI) bleeding can be characterized based on the characteristics of the bowel movements these patients present with. Bright red blood per rectum is usually associated with a lower bleed; if brisk and significant enough, however, upper bleeds can present similarly. Melenic or "tar-colored" bowel movements are more likely to occur from upper bleeds as the color is secondary to digestion of hemoglobin as it passes through the GI tract. At times, there can be a mix of the two which can make a clinical decision for intervention less obvious. To make matters more difficult, some of these patients can be on anticoagulation therapy for a myriad of reasons. Risks versus benefits at these times need to be weighed as holding this therapy may make the patients more prone to clotting while continuation would increase likelihood of bleeding. We present a case of a hypercoagulable patient who was started on rivaroxaban for history of pulmonary embolism; this led to the onset of an acute GI bleed from a duodenal diverticulum requiring endoscopic intervention. Although this can be a known effect of the therapy, the severity of bleed and changes in hemodynamics can warrant very different management strategies.
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Abraham, Neena S.
;
Barkun, Alan N.
论文数: 0引用数: 0
h-index: 0
机构:
McGill Univ, Dept Med, Div Gastroenterol, Montreal, PQ, CanadaMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Barkun, Alan N.
;
Sauer, Bryan G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Virginia, Div Gastroenterol & Hepatol, Charlottesville, VA USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Sauer, Bryan G.
;
论文数: 引用数:
h-index:
机构:
Douketis, James
;
Laine, Loren
论文数: 0引用数: 0
h-index: 0
机构:
Yale Sch Med, New Haven, CT USA
Virginia Connecticut Healthcare Syst, West Haven, CT USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Laine, Loren
;
Noseworthy, Peter A.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Dept Cardiovasc Dis, Electrophysiol, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Noseworthy, Peter A.
;
Telford, Jennifer J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, St Pauls Hosp, Div Gastroenterol, Dept Med, Vancouver, BC, CanadaMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Telford, Jennifer J.
;
Leontiadis, Grigorios, I
论文数: 0引用数: 0
h-index: 0
机构:
McMaster Univ, Div Gastroenterol, Hamilton, ON, Canada
McMaster Univ, Farncombe Family Digest Hlth Res Inst, Dept Med, Hamilton, ON, CanadaMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
机构:
Division of Digestive Diseases, Center for Esophageal Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095Division of Digestive Diseases, Center for Esophageal Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095
Ghassemi K.A.
;
Jensen D.M.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Medicine at UCLA, West Los Angeles VA Medical Centers, David Geffen School of Medicine at UCLA, Los Angeles, CA 90073-1003Division of Digestive Diseases, Center for Esophageal Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095
机构:
Henry Ford Hlth Syst, Dept Colon & Rectal Surg, Detroit, MI 48202 USAHenry Ford Hlth Syst, Dept Colon & Rectal Surg, Detroit, MI 48202 USA
Ilyas, Mohammed Iyoob Mohammed
;
Szilagy, Eric J.
论文数: 0引用数: 0
h-index: 0
机构:
Henry Ford Hlth Syst, West Bloomfield Hosp, Dept Colon & Rectal Surg, 2799 West Grand Blvd, Detroit, MI 48202 USAHenry Ford Hlth Syst, Dept Colon & Rectal Surg, Detroit, MI 48202 USA
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Abraham, Neena S.
;
Barkun, Alan N.
论文数: 0引用数: 0
h-index: 0
机构:
McGill Univ, Dept Med, Div Gastroenterol, Montreal, PQ, CanadaMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Barkun, Alan N.
;
Sauer, Bryan G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Virginia, Div Gastroenterol & Hepatol, Charlottesville, VA USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Sauer, Bryan G.
;
论文数: 引用数:
h-index:
机构:
Douketis, James
;
Laine, Loren
论文数: 0引用数: 0
h-index: 0
机构:
Yale Sch Med, New Haven, CT USA
Virginia Connecticut Healthcare Syst, West Haven, CT USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Laine, Loren
;
Noseworthy, Peter A.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Dept Cardiovasc Dis, Electrophysiol, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Noseworthy, Peter A.
;
Telford, Jennifer J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, St Pauls Hosp, Div Gastroenterol, Dept Med, Vancouver, BC, CanadaMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
Telford, Jennifer J.
;
Leontiadis, Grigorios, I
论文数: 0引用数: 0
h-index: 0
机构:
McMaster Univ, Div Gastroenterol, Hamilton, ON, Canada
McMaster Univ, Farncombe Family Digest Hlth Res Inst, Dept Med, Hamilton, ON, CanadaMayo Clin, Div Gastroenterol & Hepatol, Dept Med, Scottsdale, AZ 85259 USA
机构:
Division of Digestive Diseases, Center for Esophageal Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095Division of Digestive Diseases, Center for Esophageal Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095
Ghassemi K.A.
;
Jensen D.M.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Medicine at UCLA, West Los Angeles VA Medical Centers, David Geffen School of Medicine at UCLA, Los Angeles, CA 90073-1003Division of Digestive Diseases, Center for Esophageal Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095
机构:
Henry Ford Hlth Syst, Dept Colon & Rectal Surg, Detroit, MI 48202 USAHenry Ford Hlth Syst, Dept Colon & Rectal Surg, Detroit, MI 48202 USA
Ilyas, Mohammed Iyoob Mohammed
;
Szilagy, Eric J.
论文数: 0引用数: 0
h-index: 0
机构:
Henry Ford Hlth Syst, West Bloomfield Hosp, Dept Colon & Rectal Surg, 2799 West Grand Blvd, Detroit, MI 48202 USAHenry Ford Hlth Syst, Dept Colon & Rectal Surg, Detroit, MI 48202 USA