Life-Threatening Subglottic Thrombus Formation after Administration of Nebulized Tranexamic Acid

被引:0
作者
Awadallah, Andrew [1 ]
Armstrong, Michael [2 ]
Aden, Aisha [1 ]
Weidermann, Joshua [2 ]
Bayan, Semirra L. [2 ]
Ekbom, Dale C. [2 ,3 ]
机构
[1] Mayo Clin, Alix Sch Med, Rochester, MN USA
[2] Mayo Clin, Dept Otolaryngol Head & Neck Surg, Rochester, MN USA
[3] Mayo Clin, Alix Sch Med, 200 1st St SW, Rochester, MN 55905 USA
关键词
hemoptysis; laser wedge excision; nebulized tranexamic acid; subglottic stenosis; thrombus;
D O I
10.1002/lary.30973
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
We present a case of subglottic thrombus formation after administration of nebulized tranexamic acid (TXA) for postoperative hemoptysis following CO2 laser wedge excision of subglottic stenosis. Although other factors certainly could have resulted in postoperative bleeding and subsequent thrombus formation, the patient's rapid decompensation following administration of nebulized TXA suggests a direct effect. We recommend implementing an airway action plan regarding TXA use for patients presenting to the emergency department with postoperative hemorrhage following otolaryngology procedures.image Laryngoscope, 2023
引用
收藏
页码:1356 / 1358
页数:3
相关论文
共 5 条
[1]  
Agustin M., 2020, CASE REP PULMONOL, V2020
[2]   Coagulation and anticoagulation in idiopathic pulmonary fibrosis [J].
Crooks, Michael G. ;
Hart, Simon P. .
EUROPEAN RESPIRATORY REVIEW, 2015, 24 (137) :392-399
[3]   Intrabronchial Administration of Activated Recombinant Factor VII in a Young Child With Diffuse Alveolar Hemorrhage [J].
Larcombe, P. J. ;
Kapur, N. ;
Fraser, C. J. ;
Coulthard, M. G. ;
Schlapbach, L. J. .
PEDIATRIC BLOOD & CANCER, 2014, 61 (03) :570-571
[4]   Complications following laser wedge excision for idiopathic subglottic stenosis [J].
Richards, Bradley A. ;
Xie, Katherine Z. ;
Bowen, Andrew Jay ;
Aden, Aisha ;
Wiedermann, Joshua ;
Rutt, Amy L. ;
Vassallo, Robert ;
Edell, Eric S. ;
Bayan, Semirra L. ;
Kasperbauer, Jan L. ;
Ekbom, Dale C. .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2022, 43 (06)
[5]   Inhaled Tranexamic Acid for Hemoptysis Treatment A Randomized Controlled Trial [J].
Wand, Ori ;
Guber, Elad ;
Guber, Alexander ;
Shochet, Gali Epstein ;
Israeli-Shani, Lilach ;
Shitrit, David .
CHEST, 2018, 154 (06) :1379-1384