Metabolic Reprogramming By PRDM16 Drives Cytarabine Resistance in Acute Myeloid Leukemia

被引：1

作者：

Ikeda, Junji ^{[1
,2
]}

Kunimoto, Hiroyoshi ^{[2
]}

Saito, Yusuke ^{[3
]}

Tsujimoto, Shin-Ichi ^{[1
]}

Kurosawa, Takayuki ^{[1
]}

Takeuchi, Masanobu ^{[1
]}

Miura, Ayaka ^{[2
]}

Murakami, Koichi ^{[4
]}

Kato, Ikuma ^{[5
]}

Hishiki, Takako ^{[6
]}

Hayakawa, Noriyo ^{[6
,7
]}

Matsuura, Tomomi ^{[6
,7
]}

Funakoshi-Tago, Megumi ^{[8
]}

Yokoyama, Akihiko ^{[9
]}

Yoshida, Kenichi ^{[10
]}

Tomizawa, Daisuke ^{[11
]}

Miyano, Satoru ^{[12
]}

Tawa, Akio ^{[13
]}

Adachi, Souichi ^{[14
]}

Ogawa, Seishi ^{[15
,16
]}

Hayashi, Yasuhide ^{[17
]}

Shiba, Norio ^{[18
]}

Tamura, Tomohiko ^{[4
]}

Ito, Shuichi ^{[1
]}

Nakajima, Hideaki ^{[2
]}

机构：

[1] Yokohama City Univ, Grad Sch Med, Dept Pediat, Yokohama, Japan

[2] Yokohama City Univ, Grad Sch Med, Dept Stem Cell & Immune Regulat, Yokohama, Japan

[3] Hokkaido Univ Hosp, Div Clin Canc Genom, Sapporo, Japan

[4] Yokohama City Univ, Dept Immunol, Grad Sch Med, Yokohama, Japan

[5] Yokohama City Univ, Dept Mol Pathol, Grad Sch Med, Yokohama, Japan

[6] Keio Univ, Dept Biochem, Sch Med, Tokyo, Japan

[7] Keio Univ, Clin & Translat Res Ctr, Sch Med, Tokyo, Japan

[8] Keio Univ, Div Hygien Chem, Fac Pharm, Tokyo, Japan

[9] Natl Canc Ctr, Tsuruoka Metabol Lab, Yamagata, Japan

[10] Natl Canc Ctr, Div Canc Evolut, Tokyo, Japan

[11] Natl Ctr Child Hlth & Dev, Childrens Canc Ctr, Div Leukemia & Lymphoma, Tokyo, Japan

[12] Tokyo Med & Dent Univ, Dept Integrated Analyt, M&D Data Sci Ctr, Tokyo, Japan

[13] Higashiosaka Aramoto Heiwa Clin, Dept Pediat, Higashiosaka, Japan

[14] Kyoto Univ, Grad Sch Med, Dept Human Hlth Sci, Kyoto, Japan

[15] Kyoto Univ, Inst Adv Study Human Biol WPI ASHBi, Kyoto, Japan

[16] Kyoto Univ, Dept Pathol & Tumor Biol, Grad Sch Med, Kyoto, Japan

[17] Gunma Childrens Med Ctr, Dept Hematol Oncol, Shibukawa, Japan

[18] Yokohama City, Univ Grad Sch Med, Dept Pediat, Yokohama, Kanagawa, Japan

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-181740

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4