The effect of low molecular weight heparin combined with air pressure in the prevention of lower extremity venous thrombosis after cesarean section: A single-center retrospective study

被引:5
作者
Guo, Jian [1 ]
Li, Chenhao [1 ]
Yu, Peidong [1 ]
Xu, Tongjie [1 ]
Zhou, Haoge [1 ]
Chen, Hao [1 ,2 ]
机构
[1] Southwest Med Univ, Dept Vasc Surg, Affiliated Hosp, Luzhou, Peoples R China
[2] Southwest Med Univ, Affiliated Hosp, Dept Vasc Surg, Luzhou 646000, Sichuan, Peoples R China
关键词
deep vein thrombosis; low molecular weight heparin; lower extremity thrombosis; pneumatic compression therapy; VAS score; DEEP-VEIN THROMBOSIS; INTERMITTENT PNEUMATIC COMPRESSION; THROMBOEMBOLISM; PREGNANCY; THROMBOPROPHYLAXIS; EPIDEMIOLOGY; PUERPERIUM;
D O I
10.1097/MD.0000000000033475
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this study, we investigated the effect of low-molecular-weight heparin combined with pneumatic pressure in preventing lower extremity deep vein thrombosis after cesarean section, as well as on the visual analog scale (VAS) score. 120 women who underwent cesarean sections at full term in our hospital from January 2019 to January 2022 were included and divided into a control group (55 cases) and an observation group (65 cases) based on the different treatment methods: the control group was treated with low-molecular-weight heparin and the observation group was treated with pneumatic compression therapy based on the control group. The 2 groups were analyzed for thrombosis, clinical efficacy of the treatment methods, and VAS scores. The incidence of deep vein thrombosis in the observation group were significantly lower than in the control group (4.62% vs 21.82%, P < .05). There were no statistically significant differences in activated partial thromboplastin time, prothrombin time, and thrombin time between the 2 groups (P > .05) before treatment; however, after treatment, activated partial thromboplastin time, prothrombin time, and thrombin time in the observation group were significantly higher than those in the control group (P < .05). The clinical efficacy was significantly higher in the observation group compared with the control group (95.38% vs 78.18%, respectively). The VAS scores in the observation group were significantly lower than those in the control group (P < .05). Hence, low-molecular-weight heparin combined with pneumatic pressure therapy significantly reduces the incidence of lower limb deep vein thrombosis after cesarean section. It also improves the coagulation index and reduces post-operative pain. Therefore, it should be considered for use in clinical practice.
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页数:6
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