Role of the PLASMIC Score in the Management of Thrombotic Thrombocytopenic Purpura

被引：2

作者：

Vyas, Abhinav ^{[1
]}

Isaac, Sangeetha ^{[1
]}

Kaur, Dania ^{[1
]}

Yadav, Udit ^{[2
]}

机构：

[1] North Alabama Med Ctr, Dept Internal Med, Florence, AL 35630 USA

[2] Mayo Clin, Dept Hematol, Rochester, MN USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 03期

关键词：

hemolytic anemia; thrombotic coagulopathy; therapeutic plasma exchange (tpe); plasmic; acquired ttp; plasmic score; HEMOLYTIC-UREMIC SYNDROME; FACTOR-CLEAVING PROTEASE;

D O I：

10.7759/cureus.36188

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the case of a middle-aged male presenting with fatigue and abdominal pain. Prompt investigations demonstrated microangiopathic hemolytic anemia and thrombocytopenia on a peripheral blood smear. Thrombotic thrombocytopenic purpura was suspected based on the PLASMIC score. The patient significantly improved with therapeutic plasma exchange and prednisone within the next few days. The disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13 levels reduction is a definitive hallmark leading to microvascular thrombosis. However, some medical centers in the United States do not promptly have quick allowance to the levels. Hence, the PLASMIC score becomes imminent in initiating immediate management and preventing life-threatening complications.

引用

页数：5

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