A multimodal dataset of real world mobility activities in Parkinson's disease

被引:8
作者
Morgan, Catherine [1 ,2 ]
Tonkin, Emma L. [3 ]
Masullo, Alessandro [3 ]
Jovan, Ferdian [3 ,4 ]
Sikdar, Arindam [3 ,5 ]
Khaire, Pushpajit [3 ,6 ]
Mirmehdi, Majid [3 ]
McConville, Ryan [3 ]
Tourte, Gregory J. L. [3 ,7 ]
Whone, Alan [1 ,2 ]
Craddock, Ian [3 ]
机构
[1] Southmead Hosp, Bristol Brain Ctr, North Bristol NHS Trust, Movement Disorders Grp, Southmead Rd, Bristol BS10 5NB, England
[2] Univ Bristol, Translat Hlth Sci, 5 Tyndall Ave, Bristol BS8 1UD, England
[3] Univ Bristol, Fac Engn, Digital Hlth Off, 1 Cathedral Sq, Bristol BS1 5DD, England
[4] Univ Aberdeen, Sch Nat & Comp Sci, Aberdeen, Scotland
[5] Edge Hill Univ, Ormskirk, England
[6] Datta Meghe Inst Higher Educ & Res, Wardha, India
[7] Univ Oxford, Adv Res Comp, Oxford, England
基金
英国工程与自然科学研究理事会; 英国惠康基金;
关键词
RATING-SCALE; GAIT; PROGRESSION; RELIABILITY; MEDICATION; SYMPTOMS; UPDRS; TASK; GO;
D O I
10.1038/s41597-023-02663-5
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Parkinson's disease (PD) is a neurodegenerative disorder characterised by motor symptoms such as gait dysfunction and postural instability. Technological tools to continuously monitor outcomes could capture the hour-by-hour symptom fluctuations of PD. Development of such tools is hampered by the lack of labelled datasets from home settings. To this end, we propose REMAP (REal-world Mobility Activities in Parkinson's disease), a human rater-labelled dataset collected in a home-like setting. It includes people with and without PD doing sit-to-stand transitions and turns in gait. These discrete activities are captured from periods of free-living (unobserved, unstructured) and during clinical assessments. The PD participants withheld their dopaminergic medications for a time (causing increased symptoms), so their activities are labelled as being "on" or "off" medications. Accelerometry from wrist-worn wearables and skeleton pose video data is included. We present an open dataset, where the data is coarsened to reduce re-identifiability, and a controlled dataset available on application which contains more refined data. A use-case for the data to estimate sit-to-stand speed and duration is illustrated.
引用
收藏
页数:18
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