Childhood Obesity: An Updated Review

被引:29
作者
Leung, Alexander K. C. [1 ]
Wong, Alex H. C. [2 ]
Hon, Kam Lun [3 ,4 ]
机构
[1] Univ Calgary, Alberta Childrens Hosp, Dept Pediat, Calgary, AB, Canada
[2] Univ Calgary, Dept Family Med, Calgary, AB, Canada
[3] Chinese Univ Hong Kong, Dept Paediat, Hong Kong, Peoples R China
[4] Hong Kong Childrens Hosp, Dept Paediat & Adolescent Med, Hong Kong, Peoples R China
关键词
Diabetes mellitus; dyslipidemia; hypertension; non-alcoholic fatty liver disease; obesity; obstructive sleep apnea; overweight; BODY-MASS INDEX; CARDIOVASCULAR RISK-FACTORS; OBSTRUCTIVE SLEEP-APNEA; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; FOCAL SEGMENTAL GLOMERULOSCLEROSIS; HIGH BLOOD-PRESSURE; FREE FATTY-ACIDS; PEDIATRIC OBESITY; INSULIN-RESISTANCE; OVERWEIGHT CHILDREN;
D O I
10.2174/1573396318666220801093225
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background: Childhood obesity is an important and serious public health problem worldwide.Objective: This article aims to familiarize physicians with the evaluation, management, and prevention of childhood.Methods: A PubMed search was conducted in May, 2021, in Clinical Queries using the key terms "obesity" OR "obese". The search included clinical trials, randomized controlled trials, case-control studies, cohort studies, meta-analyses, observational studies, clinical guidelines, case reports, case series, and reviews. The search was restricted to English literature and children. The information retrieved from the above search was used in the compilation of the present article.Results: Most obese children have exogenous obesity characterized by a growth rate for height above the 50th percentile, normal intelligence, normal genitalia, and lack of historical or physical evidence of an endocrine abnormality or a congenital syndrome. Obese children are at risk for dyslipidemia, hypertension, diabetes mellitus, non-alcoholic fatty liver disease, obstructive sleep apnea, psychosocial disturbances, impaired quality of life, and shorter life expectancy. The multitude of serious comorbidities necessitates effective treatment modalities. Dietary modification, therapeutic exercise, and behavioral modification are the fundamentals of treatment. Pharmacotherapy and/or bariatric surgery should be considered for obese individuals who do not respond to the above measures and suffer from a serious comorbid condition.Conclusion: Childhood obesity, once established, is often refractory to treatment. Most treatment programs lead to a brief period of weight loss, followed by rapid re-accumulation of the lost weight after the termination of therapy. As such, preventive activity is the key to solving the problem of childhood obesity. Childhood obesity can be prevented by promoting a healthy diet, regular physical activity, and lifestyle modification. Parents should be encouraged to get involved in school and community programs that improve their children's nutritional status and physical activity.
引用
收藏
页码:2 / 26
页数:25
相关论文
共 397 条
  • [1] Proteinuria and focal segmental glomerulosclerosis in severely obese adolescents
    Adelman, RD
    Restaino, IG
    Alon, US
    Blowey, DL
    [J]. JOURNAL OF PEDIATRICS, 2001, 138 (04) : 481 - 485
  • [2] Obesity in Children: Definition, Etiology and Approach
    Aggarwal, Bhawana
    Jain, Vandana
    [J]. INDIAN JOURNAL OF PEDIATRICS, 2018, 85 (06) : 463 - 471
  • [3] Risk factors for childhood overweight: A prospective study from birth to 9.5 years
    Agras, WS
    Hammer, LD
    McNicholas, F
    Kraemer, HC
    [J]. JOURNAL OF PEDIATRICS, 2004, 145 (01) : 20 - 25
  • [4] Role of Obesity in Otitis Media in Children
    Ahmed, Sameer
    Arjmand, Ellis
    Sidell, Douglas
    [J]. CURRENT ALLERGY AND ASTHMA REPORTS, 2014, 14 (11) : 1 - 5
  • [5] An alarmingly high and increasing prevalence of obesity in Jordan
    Ajlouni, Kamel
    Khader, Yousef
    Batieha, Anwar
    Jaddou, Hashem
    El-Khateeb, Mohammed
    [J]. EPIDEMIOLOGY AND HEALTH, 2020, 42
  • [6] Low family income and food insufficiency in relation to overweight in US children - Is there a paradox?
    Alaimo, K
    Olson, CM
    Frongillo, EA
    [J]. ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 2001, 155 (10): : 1161 - 1167
  • [7] Maternal Obesity as a Risk Factor for the Development of Total Anomalous Pulmonary Venous Connection in Their Offspring
    Alvarado-Terrones, Evelyn G.
    Perea-Cabrera, Maryangel
    Klunder-Klunder, Miguel
    Segura-Stanford, Begona
    Erdmenger-Orellana, Julio R.
    Lopez-Yanez Blanco, Arturo
    Hernandez-Carbajal, Elizabeth
    Granados Riveron, Javier T.
    Mejia-Marin, Leonardo J.
    Balderrabano-Saucedo, Norma A.
    Contreras-Ramos, Alejandro
    Diaz-Rosas, Guadalupe
    Sanchez-Urbina, Rocio
    [J]. ARCHIVES OF MEDICAL RESEARCH, 2018, 49 (02) : 109 - 113
  • [8] Childhood obesity and school absenteeism: a systematic review and meta-analysis
    An, R.
    Yan, H.
    Shi, X.
    Yang, Y.
    [J]. OBESITY REVIEWS, 2017, 18 (12) : 1412 - 1424
  • [9] An Ruopeng, 2017, Int J Adolesc Med Health, V29, DOI 10.1515/ijamh-2015-0045
  • [10] Getting the dose right for obese children
    Anderson, Brian J.
    Holford, Nick H. G.
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD, 2017, 102 (01) : 54 - 55