Treatment outcomes and its associated factors among pneumonia patients admitted to public hospitals in Harar, eastern Ethiopia: a retrospective follow-up study

被引:4
作者
Jambo, Abera [1 ]
Gashaw, Tigist [2 ]
Mohammed, Ammas Siraj [1 ]
Edessa, Dumessa [1 ]
机构
[1] Haramaya Univ, Clin Pharm Dept, Dire Dawa, Ethiopia
[2] Haramaya Univ, Dept Pharmacol & Toxicol, Dire Dawa, Ethiopia
来源
BMJ OPEN | 2023年 / 13卷 / 02期
关键词
Treatment outcome; Pneumonia; Hospital; Harar; Eastern Ethiopia; COMMUNITY-ACQUIRED PNEUMONIA; SEVERE ACUTE MALNUTRITION; HEART-FAILURE; RISK-FACTORS; CHILDREN; IMPACT; ADULTS; EPIDEMIOLOGY; PREDICTORS; MORTALITY;
D O I
10.1136/bmjopen-2022-065071
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectiveAlthough there is a high risk of drug resistance, empiric treatment is a common approach for pneumonia management. In this respect, it is relevant to know treatment outcomes of patients with pneumonia. This study aimed to assess treatment outcomes and its associated factors among pneumonia patients treated at two public hospitals in Harar, eastern Ethiopia. DesignRetrospective follow-up study. SettingJugal General Hospital and Hiwot Fana Specialised University Hospital in Harar, eastern Ethiopia. ParticipantsPatients admitted and treated for pneumonia in the two public hospitals in eastern Ethiopia between April 2020 and April 2021. Primary outcomeThe primary outcome was unfavourable treatment outcome (died or transferred to intensive care unit) for pneumonia patients. ResultsA total of 693 patients with pneumonia were included in the study. 88 (12.7%) of these patients had an unfavourable treatment outcome, which included 14 (2%) transfers to the intensive care unit and 74 (10.7%) deaths. Patients with comorbidity (adjusted OR, AOR=2.96; 95% CI: 1.47 to 5.97) and with clinical features including abnormal body temperature (AOR=4.03; 95% CI: 2.14 to 7.58), tachycardia (AOR=2.57; 95% CI: 1.45 to 4.55), bradypnoea or tachypnoea (AOR=3.92; 95% CI:1.94 to 7.92), oxygen saturation below 90% (AOR=2.52; 95% CI:1.37 to 4.64) and leucocytosis (AOR=2.78, 95%, CI:1.38 to 5.58) had a significantly increased unfavourable treatment outcome. ConclusionWe found that nearly one out of eight patients with pneumonia had unfavourable treatment outcomes. It was considerably high among patients with comorbidities and apparent abnormal clinical conditions. Therefore, taking into account regionally adaptable intervention and paying close attention to pneumonia patients admitted with comorbidity and other superimposed abnormal conditions might help improve the treatment outcomes of these populations.
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页数:9
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