Development of a microfluidic-based taste sensor using lipid polymer membrane

被引:2
|
作者
Tahara, Yusuke [1 ,2 ]
Sassa, Fumihiro [3 ]
Takigawa, Ryo [3 ]
Kurihara, Yuma [1 ]
机构
[1] Shinshu Univ, Grad Sch Sci & Technol, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan
[2] Shinshu Univ, Fac Text Sci & Technol, Dept Mech Engn & Robot, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan
[3] Shinshu Univ, Shinshu Univ, Yuma Sch Sci & Technol Kurihara, Fac Text Sci & Technol, Nagano 3868567, Japan
关键词
microfuluidc device; taste sensor; chemical bonding; time dependency; ELECTRONIC TONGUE;
D O I
10.35848/1347-4065/acb4fa
中图分类号
O59 [应用物理学];
学科分类号
摘要
This study aims to develop a microfluidic-based taste sensor for detecting time-dependent human taste sensations. Lipid polymer membranes were welded to perforated polycarbonate films with organic solvents to monitor the adsorption and desorption of taste substances to lipid polymer membranes and to physically immobilize lipid polymer membranes to withstand the pressure of a pumped liquid. A polydimethylsiloxane flow channel was bonded chemically to the polycarbonate film with the lipid polymer membrane using 3-aminopropylethoxysilane. A fabricated microfluidic-based taste sensor could measure the membrane potential change with time due to the adsorption and desorption of tannic acid, an astringency substance, onto a lipid polymer membrane. The proposed sensor could be useful as a tool for assessing the time-course changes in human taste.
引用
收藏
页数:5
相关论文
共 44 条
  • [31] Detection of taste substances using impedance change in lipid/polymer membranes
    Toko, K
    Akiyama, H
    Chishaki, K
    Ezaki, S
    Iyota, T
    Yamafuji, K
    SENSORS AND MATERIALS, 1997, 9 (05) : 321 - 329
  • [32] Measurement of umami substances using multichannel taste sensor with lipid membranes
    Iiyama, S
    Iida, Y
    Toko, K
    SENSORS AND MATERIALS, 1998, 10 (08) : 475 - 485
  • [33] A Novel Taste Sensor Based on Ion Channels Incorporated in Nano-lipid Bilayer Membranes
    Liu, Qingjun
    Yu, Jinjiang
    Liu, Zongbin
    Zhang, Wei
    Wang, Ping
    Yang, Mo
    APCMBE 2008: 7TH ASIAN-PACIFIC CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING, 2008, 19 : 306 - +
  • [34] Discrimination of saltiness with coexisting components using multichannel taste sensor with lipid membranes
    Habara, M
    Toko, K
    IEICE TRANSACTIONS ON ELECTRONICS, 2000, E83C (07) : 1040 - 1045
  • [35] Development of a monitoring system for water quality using a taste sensor
    Taniguchi, A
    Naito, Y
    Maeda, N
    Sato, Y
    Ikezaki, H
    SENSORS AND MATERIALS, 1999, 11 (07) : 437 - 446
  • [36] Highly Stable Potentiometric Umami Taste Sensor Using PEDOT:SDS-Based All-Solid-State Electrode Modified With Lipid/Polymeric Membrane
    Tamara, Moch Rifqi
    Lelono, Danang
    Roto, Roto
    Wasisto, Hutomo Suryo
    Triyana, Kuwat
    IEEE SENSORS JOURNAL, 2025, 25 (01) : 175 - 183
  • [37] Selectivity control in a sweetness sensor using lipid/polymer membranes
    Cui, H
    Habara, M
    Ikezaki, H
    Toko, K
    SENSORS AND MATERIALS, 2005, 17 (07) : 385 - 390
  • [38] Development of an Artificial Lipid-Based Membrane Sensor with High Selectivity and Sensitivity to the Bitterness of Drugs and with High Correlation with Sensory Score
    Kobayashi, Yoshikazu
    Hamada, Hikari
    Yamaguchi, Yasuhiro
    Ikezaki, Hidekazu
    Toko, Kiyoshi
    IEEJ TRANSACTIONS ON ELECTRICAL AND ELECTRONIC ENGINEERING, 2009, 4 (06) : 710 - 719
  • [39] A New Method for Evaluating the Bitterness of Medicines in Development Using a Taste Sensor and a Disintegration Testing Apparatus
    Harada, Tsutomu
    Uchida, Takahiro
    Yoshida, Miyako
    Kobayashi, Yoshikazu
    Narazaki, Ryuichi
    Ohwaki, Takayuki
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 58 (08) : 1009 - 1014
  • [40] Enhancing the stability of all-solid-state astringent taste sensor through annealed solid contact and slow-drying lipid/polymeric membrane
    Tamara, Moch Rifqi
    Lelono, Danang
    Roto, Roto
    Triyana, Kuwat
    INSTRUMENTATION SCIENCE & TECHNOLOGY, 2024, 52 (06) : 731 - 746