microfuluidc device;
taste sensor;
chemical bonding;
time dependency;
ELECTRONIC TONGUE;
D O I:
10.35848/1347-4065/acb4fa
中图分类号:
O59 [应用物理学];
学科分类号:
摘要:
This study aims to develop a microfluidic-based taste sensor for detecting time-dependent human taste sensations. Lipid polymer membranes were welded to perforated polycarbonate films with organic solvents to monitor the adsorption and desorption of taste substances to lipid polymer membranes and to physically immobilize lipid polymer membranes to withstand the pressure of a pumped liquid. A polydimethylsiloxane flow channel was bonded chemically to the polycarbonate film with the lipid polymer membrane using 3-aminopropylethoxysilane. A fabricated microfluidic-based taste sensor could measure the membrane potential change with time due to the adsorption and desorption of tannic acid, an astringency substance, onto a lipid polymer membrane. The proposed sensor could be useful as a tool for assessing the time-course changes in human taste.
机构:
Eisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, JapanEisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, Japan
Harada, Tsutomu
Uchida, Takahiro
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机构:
Mukogawa Womens Univ, Sch Pharmaceut Sci, Nishinomiya, Hyogo 6638197, JapanEisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, Japan
Uchida, Takahiro
Yoshida, Miyako
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h-index: 0
机构:
Mukogawa Womens Univ, Sch Pharmaceut Sci, Nishinomiya, Hyogo 6638197, JapanEisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, Japan
Yoshida, Miyako
Kobayashi, Yoshikazu
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h-index: 0
机构:
Intelligent Sensor Technol Inc, Kanagawa 2430032, JapanEisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, Japan
Kobayashi, Yoshikazu
Narazaki, Ryuichi
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h-index: 0
机构:
Eisai & Co Ltd, Pharmaceut Sci & Technol CFU, CMC Japan, Formulat Res, Tokyo 1128088, JapanEisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, Japan
Narazaki, Ryuichi
Ohwaki, Takayuki
论文数: 0引用数: 0
h-index: 0
机构:
Eisai & Co Ltd, Customer Joy Dept, Drug Dev Technol Ctr, CEO Off, Gifu 5016195, JapanEisai & Co Ltd, CEO Off, Customer Joy Dept, Planning & Operat Sect,Bunkyo Ku, Tokyo 1128088, Japan