Development of a microfluidic-based taste sensor using lipid polymer membrane

被引:2
|
作者
Tahara, Yusuke [1 ,2 ]
Sassa, Fumihiro [3 ]
Takigawa, Ryo [3 ]
Kurihara, Yuma [1 ]
机构
[1] Shinshu Univ, Grad Sch Sci & Technol, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan
[2] Shinshu Univ, Fac Text Sci & Technol, Dept Mech Engn & Robot, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan
[3] Shinshu Univ, Shinshu Univ, Yuma Sch Sci & Technol Kurihara, Fac Text Sci & Technol, Nagano 3868567, Japan
关键词
microfuluidc device; taste sensor; chemical bonding; time dependency; ELECTRONIC TONGUE;
D O I
10.35848/1347-4065/acb4fa
中图分类号
O59 [应用物理学];
学科分类号
摘要
This study aims to develop a microfluidic-based taste sensor for detecting time-dependent human taste sensations. Lipid polymer membranes were welded to perforated polycarbonate films with organic solvents to monitor the adsorption and desorption of taste substances to lipid polymer membranes and to physically immobilize lipid polymer membranes to withstand the pressure of a pumped liquid. A polydimethylsiloxane flow channel was bonded chemically to the polycarbonate film with the lipid polymer membrane using 3-aminopropylethoxysilane. A fabricated microfluidic-based taste sensor could measure the membrane potential change with time due to the adsorption and desorption of tannic acid, an astringency substance, onto a lipid polymer membrane. The proposed sensor could be useful as a tool for assessing the time-course changes in human taste.
引用
收藏
页数:5
相关论文
共 44 条
  • [21] Study of sweet-sensitive taste sensor with lipid/polymer membranes
    Habara, Masaaki
    Hong, Cui
    Ikezaki, Hidekazu
    Toko, Kiyoshi
    RARE METAL MATERIALS AND ENGINEERING, 2006, 35 : 71 - 74
  • [22] Study of Sweet-Sensitive Taste Sensor with Lipid/Polymer Membranes
    Masaaki Habara
    Hidekazu Ikezaki
    Kiyoshi Toko
    稀有金属材料与工程, 2006, (S3) : 71 - 74
  • [23] Sensitivity-improvement of taste sensor by change of lipid concentration in membrane
    Iiyama, S.
    Ezaki, S.
    Toko, K.
    SENSORS AND ACTUATORS B-CHEMICAL, 2009, 141 (02) : 343 - 348
  • [24] A taste sensor based on surface imprinted TiO2 membrane
    Xiao, Wenxiang
    Chen, Zhencheng
    Jiang, Xingguo
    Zhao, Hongtian
    Chu, Fugang
    Hou, Hongbin
    TENTH INTERNATIONAL CONFERENCE ON PHOTONICS AND IMAGING IN BIOLOGY AND MEDICINE (PIBM 2011), 2012, 8329
  • [25] Study of the Relationship between Taste Sensor Response and the Amount of Epigallocatechin Gallate Adsorbed Onto a Lipid-Polymer Membrane
    Harada, Yuhei
    Tahara, Yusuke
    Toko, Kiyoshi
    SENSORS, 2015, 15 (03): : 6241 - 6249
  • [26] Taste Sensor Using Ionic Polymer Metal Composite
    De, Abhisek
    Pal, Anirban
    Ash, Debarshi
    Das, Kaushik
    Mondal, Kaustav
    Dhar, Pritam
    Chakraborty, Rajanya
    Rakshit, Priyanka
    Bhattacharya, Srijan
    Bepari, Bikash
    Bhaumik, Subhasis
    IEEE SENSORS LETTERS, 2021, 5 (04)
  • [27] Elucidation of Response Mechanism of a Potentiometric Sweetness Sensor with a Lipid/Polymer Membrane for Uncharged Sweeteners
    Ye, Zihong
    Ai, Tianci
    Wu, Xiao
    Onodera, Takeshi
    Ikezaki, Hidekazu
    Toko, Kiyoshi
    CHEMOSENSORS, 2022, 10 (05)
  • [28] Research on the Changes to the Lipid/Polymer Membrane Used in the Acidic Bitterness Sensor Caused by Preconditioning
    Harada, Yuhei
    Noda, Junpei
    Yatabe, Rui
    Ikezaki, Hidekazu
    Toko, Kiyoshi
    SENSORS, 2016, 16 (02)
  • [29] Relationship between the Amount of Bitter Substances Adsorbed onto Lipid/Polymer Membrane and the Electric Response of Taste Sensors
    Toko, Kiyoshi
    Hara, Daichi
    Tahara, Yusuke
    Yasuura, Masato
    Ikezaki, Hidekazu
    SENSORS, 2014, 14 (09): : 16274 - 16286
  • [30] Ion channels incorporated in nano-lipid bilayer and cell membrane for taste sensor
    Liu, Qingjun
    Yu, Jinjiang
    Hu, Zhaoyin
    Zhang, Diming
    Zhang, Qian
    Lu, Yanli
    Wang, Ping
    Yang, Mo
    OPTOELECTRONICS AND ADVANCED MATERIALS-RAPID COMMUNICATIONS, 2013, 7 (7-8): : 560 - 564