Post-discharge venous thromboembolism prophylaxis in hospitalized trauma patients: A retrospective comparison of patients receiving versus not receiving post-discharge prophylaxis

被引:2
|
作者
Belcher, Rachel M. [1 ,5 ]
Kay, Annika B. [2 ]
Fontaine, Gabriel V. [1 ]
Baldwin, Margaret [1 ]
Bledsoe, Joseph R. [4 ]
Collingridge, Dave S. [3 ]
Majercik, Sarah [2 ]
机构
[1] Intermt Med Ctr, Dept Pharm, Murray, UT USA
[2] Intermt Med Ctr, Dept Trauma & Surg Crit Care, Murray, UT 84107 USA
[3] Intermt Hlth, Res Analyt, Broomfield, CO USA
[4] Intermt Med Ctr, Dept Crit Care & Emergency Serv, 5121 South Cottonwood St, Murray, UT 84107 USA
[5] Yuma Reg Med Ctr, Dept Pharm, 2400 S Ave A, Yuma, AZ 85365 USA
来源
AMERICAN JOURNAL OF SURGERY | 2024年 / 228卷
关键词
Trauma; VTE; Prophylaxis; Thrombosis; RISK-ASSESSMENT PROFILE; PREVENTION; SURVEILLANCE; GUIDELINES; SURGERY;
D O I
10.1016/j.amjsurg.2023.10.032
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Risk of venous thromboembolism (VTE) in many trauma patients extends beyond hospitalization, but there is a paucity of evidence to guide the use of post-discharge prophylaxis (PDP). Methods: A retrospective cohort study of trauma patients deemed moderate-to-high risk for VTE (risk assessment profile score [RAP] >= 5) who were prescribed PDP based on an internal clinical guideline assessing injury pattern and mobility status. PDP patients were compared with those that did not receive post-discharge prophylaxis (NPDP). Results: 1512 patients were included. PDP group had higher mean RAP score (7.3 vs. 6.4, p < 0.001), more likely to have a complex orthopedic fracture and underwent a longer median hospital (4.7 vs. 2.9 days, p < 0.001). No difference between groups in 90-day VTE (11 [1.5 %] (PDP) vs. 8 [1.0 %] (NPDP), p = 0.50), clinically relevant bleeding (p = 0.58), or readmission (p = 0.46). Conclusions: VTE incidence, clinically relevant bleeding, and readmission 90-days after hospital discharge were low and similar between PDP and NPDP groups. PDP prescribed in a presumably higher VTE risk trauma population may mitigate the long-term risk of VTE.
引用
收藏
页码:247 / 251
页数:5
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