Ophthalmoplegia associated with anti-GQ1b antibodies: case report and review

被引:3
作者
Yvon, Camille [1 ]
Nee, Dominic [2 ]
Chan, Dennis [2 ]
Malhotra, Raman [1 ]
机构
[1] Queen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead, England
[2] Brighton & Sussex Univ Hosp NHS Trust, Neurol Dept, Brighton, E Sussex, England
来源
ORBIT-THE INTERNATIONAL JOURNAL ON ORBITAL DISORDERS-OCULOPLASTIC AND LACRIMAL SURGERY | 2023年 / 42卷 / 02期
关键词
Acute ophthalmoparesis without ataxia; GQ1b ganglioside; Guillain-Barre syndrome; ophthalmoplegia; ptosis; GUILLAIN-BARRE-SYNDROME; MILLER FISHER SYNDROME; IGG ANTIBODY; CAMPYLOBACTER-JEJUNI; GM1;
D O I
10.1080/01676830.2021.1974495
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
A 60-year-old man with longstanding bilateral asymmetrical ptosis presented with a partial third nerve palsy. His diplopia improved following an ice pack test. He did not report any symptoms related to the coronavirus disease 2019 (COVID-19), and nasopharyngeal swab was negative. Initial head imaging and blood work-up were normal except for a high titer of anti-GQ1b antibodies. The patient was subsequently diagnosed with acute ophthalmoparesis without ataxia which is part of the anti-GQ1b antibody syndrome spectrum. He made a spontaneous recovery over the following months without the need for immunotherapy. Clinical features, pathophysiology and a review of the literature are discussed herein. It is important to consider anti-GQ1b antibody syndrome in patients with symptoms of diplopia, ptosis or suspected ocular myasthenia.
引用
收藏
页码:192 / 195
页数:4
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