EUS-guided gastroenterostomy using a novel electrocautery lumen apposing metal stent for treatment of gastric outlet obstruction (with video)

被引：9

作者：

Mangiavillano, Benedetto ^{[1
,2
,14
]}

Larghi, Alberto ^{[3
]}

Vargas-Madrigal, Jorge ^{[4
]}

Facciorusso, Antonio ^{[5
]}

Di Matteo, Francesco ^{[6
]}

Crino, Stefano Francesco ^{[7
]}

Pham, Khanh Do-Cong ^{[8
]}

Moon, Jong Hoo ^{[9
]}

Auriemma, Francesco ^{[1
]}

Camellini, Lorenzo ^{[10
]}

Paduano, Danilo ^{[1
]}

Stigliano, Serena ^{[6
]}

Calabrese, Federica ^{[1
]}

Ofosu, Andrew ^{[11
]}

Al-Lehibi, Abed ^{[12
]}

Repici, Alessandro ^{[2
,13
]}

机构：

[1] Humanitas Mater Domini, Gastrointestinal Endoscopy Unit, Castellanza, Italy

[2] Humanitas Univ, Dept Biomed Sci, Milan, Italy

[3] Fdn Policlin Univ A Gemelli IRCCS, Digest Endoscopy Unit, Rome, Italy

[4] HSJD CCSS, Serv Gastroenterol, San Jose, Costa Rica

[5] Univ Foggia, Dept Med & Surg Sci, Gastroenterol Unit, Foggia, Italy

[6] Campus Bio Med Univ, Digest Endoscopy, Rome, Italy

[7] Univ Verona, Digestivee Endoscopy Unit, Verona, Italy

[8] Haukeland Hosp, Dept Med, Bergen, Norway

[9] SoonChunHyang Univ, Digest Dis Ctr, Dept Internal Med, Sch Med, Bucheon, South Korea

[10] St Andrea Hosp, Endoscop Unit, La Spezia, Italy

[11] Univ Cincinnati, Div Gastroenterol & Hepatol, Coll Med, Cincinnati, OH USA

[12] King Saud Bin Abduaziz Univ Hlth Sci, King Fahad Med City Fac Med, Riyadh, Saudi Arabia

[13] IRCCS, Humanitas Clin & Res Ctr, Rozzano, Italy

[14] Humanitas Mater Domini, Gastrointestinal Endoscopy Unit, Via Gerenzano n-2, I-21053 Castellanza, VA, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2023年 / 55卷 / 05期

关键词：

LAMS; lumen -apposing metal stent; Hot-Spaxus; EUS-guided anastomosis; EUS-GE; Interventional EUS; Gastric outlet obstruction (GOO); Malignant GOO; Benign GOO; BILIARY DRAINAGE; MANAGEMENT;

D O I：

10.1016/j.dld.2023.02.009

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background and aim: Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) for the treatment of gastric outlet obstruction (GOO) has been actually performed only with one type of electrocautery lumen -apposing metal stents (EC-LAMS). We aimed to evaluate the safety, technical and clinical effectiveness of EUS-GE using a newly available EC-LAMS in patients with malignant and benign GOO.Materials and methods: Consecutive patients who underwent EUS-GE for GOO using the new EC-LAMS at five endoscopic referral centers were retrospectively evaluated. Clinical efficacy was determined utilizing the Gastric Outlet Obstruction Scoring System (GOOSS).Results: Twenty-five patients (64% male, mean age 68.7 +/- 9.3 years) met the inclusion criteria; 21 (84%) had malignant etiology. Technically, EUS-GE was successful in all patients, with a mean procedural time of 35 +/- 5 min. Clinical success was 68% at 7 days and 100% at 30 days. The mean time to resume oral diet was 11.4 +/- 5.8 h, with an improvement of at least one point of GOOSS score observed in all patients. The median hospital stay was 4 days. No procedure-related adverse events occurred. After a mean follow-up of 7.6 months (95% CI 4.6-9.2), no stent dysfunctions were observed.Conclusion: This study suggests EUS-GE can be performed safely and successfully using the new EC-LAMS. Future large multicenter prospective studies are needed to confirm our preliminary data.(c) 2023 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：644 / 648

页数：5