Association between birth weight/joint exposure to ambient air pollutants and type 2 diabetes: a cohort study in the UK Biobank

被引：0
|
作者：
Liu, Xiaojing [1 ,2 ]
Liu, Xiaowen [1 ,2 ]
Jin, Ming [1 ,2 ]
Huang, Ninghao [1 ]
Song, Zimin [1 ]
Li, Nan [1 ,2 ,5 ]
Huang, Tao [1 ,3 ,4 ]
机构：
[1] Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing, Peoples R China
[2] Peking Univ, Inst Reprod & Child Hlth, Key Lab Reprod Hlth, Beijing, Peoples R China
[3] Peking Univ, Key Lab Mol Cardiovasc Sci, Minist Educ, Beijing, Peoples R China
[4] Peking Univ, Inst Artificial Intelligence, Ctr Intelligent Publ Hlth, Beijing, Peoples R China
[5] 38 Xueyuan Rd, Beijing 100191, Peoples R China
来源：
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH | 2024年 / 34卷 / 08期
关键词：
Type; 2; diabetes; birth weight; air pollution score; joint effect; UK biobank; LONG-TERM EXPOSURE; POLLUTION; MELLITUS; HEALTH; RISK; DISORDERS; GROWTH; LIFE; NO2;
D O I：
10.1080/09603123.2023.2278634
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Early life events and environmental factors are associated with type 2 diabetes (T2D) development. We assessed the combined effect of birth weight andambient air pollutants, and effect of their interaction on T2D risk. Totally, 6,474 T2D incidents were recorded over an 8.7-year follow-up period. The adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) were 1.31 (1.26, 1.36) for each kilogram decrease in birth weight, and 1.08 (1.05, 1.11) for each standard deviation increase in air pollution score (APS). Birth weight<3000 g amplified the T2D risk associated with high APS. A combination of the lowest birth weight (<2500 g) and the highest quintile of APS led to over two-fold increase in T2D risk (aHR: 2.17; 95% CI: 1.79-2.64). There was a significant additive interaction between them. In conclusion, ambient air pollutants increase the risk for T2D, particularly in populations with low birth weight.
引用
收藏
页码：2888 / 2898
页数：11
相关论文
共 50 条
  • [31] The Association of Ambient Air Pollution With Cataract Surgery in UK Biobank Participants: Prospective Cohort Study
    Chua, Sharon Y. L.
    Khawaja, Anthony P.
    Desai, Parul
    Rahi, Jugnoo S.
    Day, Alex C.
    Hammond, Christopher J.
    Khaw, Peng T.
    Foster, Paul J.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2021, 62 (15)
  • [32] Long-term changes in frailty and incident type 2 diabetes: A prospective cohort study based on the UK Biobank
    Sun, Ying
    Li, Weihao
    Zhou, Yinuo
    Wang, Bin
    Tan, Xiao
    Lu, Yingli
    Zhu, Jingjing
    Shi, Wentao
    Wang, Ningjian
    DIABETES OBESITY & METABOLISM, 2024, 26 (08): : 3352 - 3360
  • [33] In people with type 2 diabetes, sarcopenia is associated with the incidence of cardiovascular disease: A prospective cohort study from the UK Biobank
    Boonpor, Jirapitcha
    Pell, Jill P.
    Ho, Frederick K.
    Celis-Morales, Carlos
    Gray, Stuart R.
    DIABETES OBESITY & METABOLISM, 2024, 26 (02): : 524 - 531
  • [34] Association between exposure to ambient air pollutants and metabolic syndrome in the vicinity of the Taklamakan Desert
    Wang, Zhe
    Ji, Weidong
    Wang, Yushan
    Li, Lin
    Wang, Kai
    Liu, Hongze
    Yang, Yining
    Zhou, Yi
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2025, 290
  • [35] The Mediating Role of Placental Weight Change in the Association Between Prenatal Exposure to Thallium and Birth Weight: A Prospective Birth Cohort Study
    Zhou, He
    Sun, Xiaoli
    Wang, Yiding
    Ye, Yufeng
    Chen, Hanwei
    Chen, Qingsong
    He, Guanhao
    Wang, Jiaqi
    Liu, Xin
    Dong, Moran
    Chen, Dengzhou
    Chen, Guimin
    Yuan, Lixia
    Xiao, Jianpeng
    Hu, Jianxiong
    Zeng, Weilin
    Rong, Zuhua
    Zhang, Qianqian
    Zhou, Mengya
    Guo, Lingchuan
    Lv, Yanyun
    Fan, Jingjie
    Pu, Yudong
    Ma, Wenjun
    Zhang, Bo
    Liu, Tao
    FRONTIERS IN PUBLIC HEALTH, 2021, 9
  • [36] Association of ambient air pollution exposure with low birth weight
    Fu, Zuqiang
    Liu, Qian
    Liang, Jingjia
    Huang, Tao
    Liang, Geyu
    Zhou, Yong
    Gu, Aihua
    ENVIRONMENTAL RESEARCH, 2022, 215
  • [37] Association of oxidative balance score with incident cardiovascular disease in patients with type 2 diabetes: findings of the UK Biobank study
    Cheng, Licheng
    Wang, Xuanyang
    Dang, Keke
    Hu, Jinxia
    Zhang, Jia
    Xu, Xiaoqing
    Pan, Sijia
    Qi, Xiang
    Li, Ying
    EUROPEAN JOURNAL OF NUTRITION, 2025, 64 (03)
  • [38] Regular use of ibuprofen or paracetamol and incident type 2 diabetes: A prospective cohort study in the UK Biobank
    Zhou, Chun
    Wu, Qimeng
    Ye, Ziliang
    Zhang, Yuanyuan
    Zhang, Yanjun
    Yang, Sisi
    Liu, Mengyi
    He, Panpan
    Qin, Xianhui
    DIABETES & METABOLISM, 2022, 48 (06)
  • [39] Association between exposure to air pollution and hippocampal volume in adults in the UK Biobank
    Hedges, Dawson W.
    Erickson, Lance D.
    Kunzelman, Jackie
    Brown, Bruce L.
    Gale, Shawn D.
    NEUROTOXICOLOGY, 2019, 74 : 108 - 120
  • [40] Ambient air pollution, lifestyle, and genetic predisposition associated with type 2 diabetes: findings from a national prospective cohort study
    Li, Rui
    Cai, Miao
    Qian, Zhengmin
    Wang, Xiaojie
    Zhang, Zilong
    Wang, Chongjian
    Wang, Yuqin
    Arnold, Lauren D.
    Howard, Steven W.
    Li, Haitao
    Lin, Hualiang
    SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 849
12345