Comorbid autoimmune disorders in people with multiple sclerosis: A retrospective cohort study

被引：5
作者：
Rato, Miguel Leal [1 ,2 ]
Santos, Monica [1 ]
de Sa, Joao [1 ,3 ]
Ferreira, Joao [1 ,3 ]
机构：
[1] Hosp Santa Maria, Ctr HospUniv Lisboa Norte, Dept Neurociencias & Saude Mental, Serv Neurol, Ave Prof Egas Moniz, P- 1649035 Lisbon, Portugal
[2] Univ Lisbon, Inst Farmacol & Neurociencias, Fac Med, Lisbon, Portugal
[3] Univ Lisbon, Ctr Estudos Egas Moniz, Fac Med, Lisbon, Portugal
来源：
JOURNAL OF NEUROIMMUNOLOGY | 2023年 / 385卷
关键词：
Multiple sclerosis; Comorbidities; Autoimmunity; Immunophenotypes; DISEASE; PREVALENCE; FAMILIES; RISK;
D O I：
10.1016/j.jneuroim.2023.578226
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Most autoimmune disorders, including multiple sclerosis (MS), are influenced by shared genetic and environ-mental factors. We conducted a cohort study of people with MS to calculate the frequency of comorbid auto-immune disorders and characterize this cohort. Autoimmune diseases were present in 30 (8.6%) of 349 patients. The most prevalent diagnoses were autoimmune thyroiditis, type 1 diabetes mellitus, psoriasis, and inflamma-tory bowel disease. We found no association with demographic or clinical factors. In our cohort, autoimmune disorders were not uncommon. Identifying such comorbidities in people with MS can be determinant for un-derstanding disease mechanisms, treatment decisions and disease management.
引用
收藏
页数：4
相关论文
共 50 条
  • [41] Accuracy of FRAX® in People With Multiple Sclerosis
    Bisson, Etienne J.
    Finlayson, Marcia L.
    Ekuma, Okechukwu
    Marrie, Ruth Ann
    Leslie, William D.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2019, 34 (06) : 1095 - 1100
  • [42] Impact of parental multiple sclerosis on early childhood development: A retrospective cohort study
    Razaz, Neda
    Tremlett, Helen
    Boyce, W. Thomas
    Guhn, Martin
    Joseph, K. S.
    Marrie, Ruth Ann
    MULTIPLE SCLEROSIS JOURNAL, 2015, 21 (09) : 1172 - 1183
  • [43] Disease modifying therapy in the treatment of tumefactive multiple sclerosis: A retrospective cohort study
    Galetta, Kristin
    Ham, Andrew Siyoon
    Vishnevetsky, Anastasia
    Bhattacharyya, Shamik
    Mateen, Farrah J.
    JOURNAL OF NEUROIMMUNOLOGY, 2024, 388
  • [44] Treatment withdrawal in relapsing-remitting multiple sclerosis: a retrospective cohort study
    Lus, G.
    Signoriello, E.
    Maniscalco, G. T.
    Bonavita, S.
    Signoriello, S.
    Gallo, C.
    EUROPEAN JOURNAL OF NEUROLOGY, 2016, 23 (03) : 489 - 493
  • [45] Effects of socioeconomic status on excess mortality in patients with multiple sclerosis in France: A retrospective observational cohort study
    Wilson, Sarah
    Calocer, Floriane
    Rollot, Fabien
    Fauvernier, Mathieu
    Remontet, Laurent
    Tron, Laure
    Vukusic, Sandra
    Le Page, Emmanuelle
    Debouverie, Marc
    Ciron, Jonathan
    Ruet, Aurelie
    De Seze, Jerome
    Zephir, Helene
    Moreau, Thibault
    Lebrun-Frenay, Christine
    Laplaud, David-Axel
    Clavelou, Pierre
    Labauge, Pierre
    Berger, Eric
    Pelletier, Jean
    Heinzlef, Olivier
    Thouvenot, Eric
    Camdessanche, Jean Philippe
    Leray, Emmanuelle
    Dejardin, Olivier
    Defer, Gilles
    LANCET REGIONAL HEALTH-EUROPE, 2023, 24
  • [46] Determinants of the severity of comorbid migraine in multiple sclerosis
    Villani, Veronica
    De Giglio, Laura
    Sette, Giuliano
    Pozzilli, Carlo
    Salvetti, Marco
    Prosperini, Luca
    NEUROLOGICAL SCIENCES, 2012, 33 (06) : 1345 - 1353
  • [47] Risk factors for falling for people with Multiple Sclerosis identified in a prospective cohort study
    Quinn, Gillian
    Comber, Laura
    McGuigan, Chris
    Hannigan, Ailish
    Galvin, Rose
    Coote, Susan
    CLINICAL REHABILITATION, 2021, 35 (05) : 765 - 774
  • [48] Spasticity treatment patterns among people with multiple sclerosis: a Swedish cohort study
    Smith, Kelsi A.
    Piehl, Fredrik
    Olsson, Tomas
    Alfredsson, Lars
    Hillert, Jan
    Kockum, Ingrid
    Strid, Pernilla
    Montgomery, Scott
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023, 94 (05) : 337 - 348
  • [49] Risk of Psychiatric Disorders in Multiple Sclerosis: A Nationwide Cohort Study in an Asian Population
    Huang, Yao-Ching
    Chien, Wu-Chien
    Chung, Chi-Hsiang
    Chang, Hsin-An
    Kao, Yu-Chen
    Wan, Fang-Jung
    Huang, Shi-Hao
    Chung, Ren-Jei
    Wang, Richard S.
    Wang, Bing-Long
    Tzeng, Nian-Sheng
    Sun, Chien-An
    NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2021, 17 : 587 - 604
  • [50] An Exploration of Falls and Dual Tasking A Prospective Cohort Study of People With Multiple Sclerosis
    Quinn, Gillian
    Comber, Laura
    O' Malley, Nicola
    McGuigan, Chris
    Galvin, Rose
    Coote, Susan
    TOPICS IN GERIATRIC REHABILITATION, 2019, 35 (03) : 190 - 198
12345