Mediation of daily ambient ozone concentration on association between daily mean temperature and mortality in 7 metropolitan cities of Korea

被引:11
作者
Bae, Sanghyuk [1 ,2 ,8 ]
Lim, Youn-Hee [3 ]
Oh, Jongmin [4 ,5 ,6 ]
Kwon, Ho-Jang [7 ]
机构
[1] Catholic Univ Korea, Coll Med, Dept Prevent Med, Seoul, South Korea
[2] Catholic Univ Korea, Environm Hlth Ctr, Seoul, South Korea
[3] Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark
[4] Ewha Womans Univ, Coll Med, Dept Environm Med, Seoul, South Korea
[5] Ewha Womans Univ, Inst Ewha SCL Environm Hlth IESEH, Coll Med, Seoul, South Korea
[6] Seoul Natl Univ, Coll Med, Dept Human Syst Med, Seoul, South Korea
[7] Dankook Univ, Coll Med, Dept Prevent Med, Cheonan, South Korea
[8] 222 Banpo daero, Seoul 06591, South Korea
关键词
CLIMATE-CHANGE; AIR-POLLUTION; MORBIDITY; BURDEN;
D O I
10.1016/j.envint.2023.108078
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Background: Climate change is suspected to cause adverse health effects, and increased ozone concentration is one of the proposed pathways. We examined the mediation of ozone on the association between temperature and daily mortality and estimated excess mortality due to climate change. Methods: Daily mean temperature, 8-hour maximum ozone concentration, and daily number of non-accidental deaths from 7 metropolitan cities in Korea (Seoul, Busan, Daegu, Incheon, Daejeon, Gwangju, and Ulsan) between January 1, 2006 and December 31, 2019 were analyzed. A mediation analysis using a linear regression model for temperature and ozone and a Poisson regression model for temperature and mortality adjusting for ozone was conducted on days with temperature higher than or lower than city specific minimum mortality temperature. We calculated excess mortality due to direct and indirect effects of daily temperature exceeding average daily temperature from 1960 to 1990. Results: The daily mean temperature from 2006 to the end of 2019 was 1.15 & PLUSMN; 2.94 degrees C higher than the average daily temperature from 1960 to 1990. The pooled relative risk (for a 1 degrees C increment) of indirect effects through increased ozone were 1.0002 [95% confidence interval (CI): 0.9999, 1.0004] and 1.0003 (95% CI: 1.0002, 1.0005) in days with higher than or lower than minimum mortality temperature, respectively. The numbers of excess deaths during the study period were 2072.5 (95% CI: 1957.1, 2186.5) due to direct effects in days with higher than minimal mortality temperature, and 94.6 (95% CI: 84.3, 101.7) and 268.5 (95% CI: 258.4, 289.1) due to indirect effects in days with higher than and lower than minimal mortality temperature, respectively. Conclusion: We observed a mediating effect of ozone between temperature and daily mortality. There has been excess deaths due direct effect of temperature and indirect effects through ozone.
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页数:7
相关论文
共 31 条
[1]   Association of summer temperatures and acute kidney injury in South Korea: a case-crossover study [J].
Ahn, Joonho ;
Bae, Sanghyuk ;
Ha Chung, Byung ;
Myong, Jun-Pyo ;
Park, Min Young ;
Lim, Youn-Hee ;
Kang, Mo-Yeol .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2023, 52 (03) :774-782
[2]   The Role of Ozone as a Mediator of the Relationship Between Heat Waves and Mortality in 15 French Urban Areas [J].
Alari, Anna ;
Chen, Chen ;
Schwarz, Lara ;
Hdansen, Kristen ;
Chaix, Basile ;
Benmarhnia, Tarik .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2023, 192 (06) :949-962
[3]   Causal association between ambient ozone concentration and mortality in Seoul, Korea [J].
Bae, Sanghyuk ;
Lim, Youn-Hee ;
Hong, Yun-Chul .
ENVIRONMENTAL RESEARCH, 2020, 182
[4]   A meta-analysis of time-series studies of ozone and mortality with comparison to the national morbidity, mortality, and air pollution study [J].
Bell, ML ;
Dominici, F ;
Samet, JM .
EPIDEMIOLOGY, 2005, 16 (04) :436-445
[5]   Observed relationships of ozone air pollution with temperature and emissions [J].
Bloomer, Bryan J. ;
Stehr, Jeffrey W. ;
Piety, Charles A. ;
Salawitch, Ross J. ;
Dickerson, Russell R. .
GEOPHYSICAL RESEARCH LETTERS, 2009, 36
[6]  
Chung J.Y., 2001, J KOREAN SOC HLTH ST, V26, P3
[7]  
Doherty R.M., 2017, ENV HLTH, V16
[8]   The Role of Temperature in Modifying the Risk of Ozone-Attributable Mortality under Future Changes in Climate: A Proof-of-Concept Analysis [J].
Fann, Neal ;
Coffman, Evan ;
Jackson, Melanie ;
Jhun, Iny ;
Lamichhane, Archana P. ;
Nolte, Christopher G. ;
Roman, Henry ;
Sacks, Jason D. .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 56 (02) :1202-1210
[9]   The relation between temperature, ozone, and mortality in nine french cities during the heat wave of 2003 [J].
Filleul, Laurent ;
Cassadou, Sylvie ;
Medina, Sylvia ;
Fabres, Pascal ;
Lefranc, Agnes ;
Eilstein, Daniel ;
Le Tertre, Alain ;
Pascal, Laurence ;
Chardon, Benoit ;
Blanchard, Myriam ;
Declercq, Christophe ;
Jusot, Jean-Francois ;
Prouvost, Helene ;
Ledrans, Martine .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2006, 114 (09) :1344-1347
[10]   Mortality risk attributable to high and low ambient temperature: a multicountry observational study [J].
Gasparrini, Antonio ;
Guo, Yuming ;
Hashizume, Masahiro ;
Lavigne, Eric ;
Zanobetti, Antonella ;
Schwartz, Joel ;
Tobias, Aurelio ;
Tong, Shilu ;
Rocklov, Joacim ;
Forsberg, Bertil ;
Leone, Michela ;
De Sario, Manuela ;
Bell, Michelle L. ;
Guo, Yue-Liang Leon ;
Wu, Chang-fu ;
Kan, Haidong ;
Yi, Seung-Muk ;
Zanotti Stagliorio Coelho, Micheline de Sousa ;
Nascimento Saldiva, Paulo Hilario ;
Honda, Yasushi ;
Kim, Ho ;
Armstrong, Ben .
LANCET, 2015, 386 (9991) :369-375