Diagnosis and Current Treatment of Aneurysmal Bone Cysts

被引:3
作者
Bakarman, Khalid A. [1 ]
机构
[1] King Saud Univ, Orthopaed Surg, Riyadh, Saudi Arabia
关键词
aneurysmal bone cysts; benign bone tumor; abc; curettage; bone tumor; CELL REPARATIVE GRANULOMA; PERCUTANEOUS ETHIBLOC INJECTION; SOLID VARIANT; SURGICAL-TREATMENT; PRIMARY LESIONS; RECURRENCE RATE; TUBULAR BONES; SECONDARY; CURETTAGE; CHILDREN;
D O I
10.7759/cureus.53587
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The purpose of this review is to increase awareness about the evolution and development of current trends in the diagnosis and treatment of aneurysmal bone cysts (ABCs). ABCs are benign, but locally aggressive bone tumors that mainly affect children. ABCs comprise 1% of all primary bone tumors and occur most frequently during the first two decades of life. The diagnosis is made using a variety of imaging modalities and has the characteristic features of an expansile, radiolucent lesion that is often seen in the metaphyseal region of the bone and has fluid -fluid levels that are apparent on MRI. In the pediatric population, telangiectatic osteosarcoma and unicameral bone cyst (UBC) are the main differential diagnoses of an ABC. Giant cell tumors (GCTs) also include in differential diagnosis, which often manifest in patients older than 15 and do not penetrate the open physis although they develop after the physeal closure. Imaging alone cannot rule out telangiectatic osteosarcoma; therefore, a biopsy is recommended. A variety of treatment options have been described; traditionally, most patients are treated with curettage and bone grafting. Curettage alone, however, usually results in tumor recurrence following excision. A variety of adjuvants have been utilized with varying degrees of effectiveness to reduce the risk of local recurrence. When a cyst is in the pelvis, its location and size are such that surgery is a very risky option. Selective arterial embolization has significantly contributed to the development of effective treatments for these situations. Embolization or radiation, as well as denosumab therapy, are widely used as therapies for ABCs in anatomic locations where surgery would significantly increase morbidity.
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页数:12
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[41]   Unicameral (simple) and aneurysmal bone cysts: the effect of insufficient curettage on recurrence [J].
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[44]   Treatment of Aneurysmal Bone Cysts by Minimally Invasive Curettage and Allogenic Bone Impaction Grafting: Mid-to Long-term Results [J].
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[45]   Subperiosteal resection of aneurysmal bone cysts of the distal fibula [J].
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[46]   Update on aneurysmal bone cyst: pathophysiology, histology, imaging and treatment [J].
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[48]   ANEURYSMAL BONE-CYSTS OF THE SPINE [J].
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Mohammed, R. ;
Grimer, R. J. .
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[50]   Metachronous multiple aneurysmal bone cysts [J].
Sundaram, M ;
McDonald, DJ ;
Steigman, CK ;
Bocchini, T .
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