Correlation between the perineural invasion and neck metastasis in patients with laryngeal carcinoma: a cross sectional study

被引：0

作者：

Hamela, Mo'men Ali ^{[1
]}

Bestawy, Ahmed ^{[1
]}

Gharib, Fadi ^{[1
]}

机构：

[1] Cairo Univ, Kasr Alainy Sch Med, Dept Otolaryngol, 71 El Kasr El Aini St, Giza 11562, Egypt

来源：

EGYPTIAN JOURNAL OF OTOLARYNGOLOGY | 2023年 / 39卷 / 01期

关键词：

Laryngeal squamous cell carcinoma; Perineural invasion; Nodal metastasis; SQUAMOUS-CELL CARCINOMA; HEAD; CANCER; SPREAD;

D O I：

10.1186/s43163-023-00444-w

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

BackgroundOne of the most problematic issues of laryngeal carcinoma is recurrence after surgery one of the causes of recurrence this study tries to find its relevance is the peri neural invasion.Aim of the workTo determine whether there is a relationship between perineural invasion and cervical nodal metastases of laryngeal squamous cell carcinoma.MethodsBetween December 2019 and September 2020, this study was conducted on 30 individuals who had laryngeal SCC. After the surgical removal of the tumor, a histological examination was done to check for the existence of perineural invasion, which was later linked to the cervical nodal metastases.ResultsOf our patients 26.7% (8/30) had perineural invasion. Perineural invasion and cervical nodal metastasis were statistically significantly associated (P value = 0.018).ConclusionA strong histologic predictor of cervical nodal metastases is perineural invasion.

引用

页数：6

共 50 条

[31] Perineural Invasion in T1 Oral Squamous Cell Carcinoma Indicates the Need for Aggressive Elective Neck Dissection [J].

Tai, Shyh-Kuan ;

Li, Wing-Yin ;

Yang, Muh-Hwa ;

Chu, Pen-Yuan ;

Wang, Yi-Fen .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2013, 37 (08) :1164-1172

[32] Surgical resection for clinical perineural invasion from cutaneous squamous cell carcinoma of the head and neck [J].

Panizza, Benedict ;

Solares, C. Arturo ;

Redmond, Michael ;

Parmar, Priya ;

O'Rourke, Peter .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2012, 34 (11) :1622-1627

[33] Sentinel lymph node metastasis in primary cutaneous basosquamous carcinoma. A cross-sectional study [J].

Kakagia, Despoina D. ;

Zapandioti, Polyxeni ;

Trypsiannis, Grigoris ;

Grekou, Alexandra N. ;

Tsoutsos, Dimosthenis .

JOURNAL OF SURGICAL ONCOLOGY, 2018, 117 (08) :1752-1758

[34] Radiation therapy for low- and high-risk perineural invasion in head and neck cutaneous squamous cell carcinoma: Clinical outcomes and patterns of failure [J].

Gobillot, Theodore A. ;

Greer, Matthew ;

Parvathaneni, Upendra ;

Liao, Jay J. ;

Laramore, George E. ;

Goff, Peter ;

Wallner, Kent ;

Rodriguez, Cristina P. ;

Houlton, Jeffrey J. ;

Barber, Brittany R. ;

Futran, Neal D. ;

Rizvi, Zain H. .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2023, 45 (09) :2323-2334

[35] Perineural Invasion Is Associated With Function-evoked Pain and Altered Extracellular Matrix in Patients With Head and Neck Squamous Cell Carcinoma [J].

Santi, Maria D. ;

Zhang, Morgan ;

Asam, Kesava ;

Yu, Gary ;

Dong, Phuong M. ;

Sheehan, Delaney H. ;

Aouizerat, Bradley E. ;

Thomas, Carissa M. ;

Viet, Chi T. ;

Ye, Yi .

JOURNAL OF PAIN, 2024, 25 (10)

[36] Diffuse pattern, orbital invasion, perineural invasion and Ki-67 are associated with nodal metastasis in patients with eyelid sebaceous carcinoma [J].

Gu, Xiang ;

Xie, Minyue ;

Luo, Yingxiu ;

Song, Xin ;

Xu, Shiqiong ;

Fan, Xianqun .

BRITISH JOURNAL OF OPHTHALMOLOGY, 2023, 107 (06) :756-762

[37] Epidemiology of Clinical Perineural Invasion in Cutaneous Squamous Cell Carcinoma of the Head and Neck [J].

Solares, C. Arturo ;

Lee, Ken ;

Parmar, Priya ;

O'Rourke, Peter ;

Panizza, Benedict .

OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2012, 146 (05) :746-751

[38] Management of the N0 neck in patients with laryngeal squamous cell carcinoma [J].

Shi, Yong ;

Zhou, Liang ;

Tao, Lei ;

Zhang, Ming ;

Chen, Xiao-Ling ;

Li, Cai ;

Gong, Hong-Li .

ACTA OTO-LARYNGOLOGICA, 2019, 139 (10) :908-912

[39] Incidence of level IIB lymph node metastasis in supraglottic laryngeal squamous cell carcinoma with clinically negative neck-A prospective study [J].

Jia, Shenshan ;

Wang, Yanying ;

He, Hongjiang ;

Xiang, Cheng .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2013, 35 (07) :987-991

[40] Expression of ezrin and moesin related to invasion, metastasis and prognosis of laryngeal squamous cell carcinoma [J].

Wang, X. ;

Liu, M. ;

Zhao, C. Y. .

GENETICS AND MOLECULAR RESEARCH, 2014, 13 (03) :8002-8013

← 1 2 3 4 5 →