Copper-catalyzed bifunctionalization of alkenes with anilines and HFIP: Efficient access to 1,3-amino alcohols

被引：4

作者：

Zhu, Fengxiang ^{[1
]}

Deng, Peng ^{[1
]}

Zhang, Pengbo ^{[2
]}

机构：

[1] Shanxi Univ, Sch Chem & Chem Engn, Wucheng Rd 92, Taiyuan 030006, Peoples R China

[2] Xinxiang Med Univ, Sch Publ Hlth, Xinxiang 453003, Peoples R China

来源：

JOURNAL OF CATALYSIS | 2024年 / 429卷

基金：

中国国家自然科学基金;

关键词：

Copper; Bifunctionalization; Alkenes; C-H activation; 3-amino alcohols; C-H AMINATION; STEREOSELECTIVE-SYNTHESIS; ASYMMETRIC HYDROGENATION; DIASTEREOSELECTIVE SYNTHESIS; BETA-KETOENAMIDES; FUNCTIONALIZATION; KETONES; BONDS; CARBON; 1,3-OXAZINANES;

D O I：

10.1016/j.jcat.2024.115292

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An interesting copper-catalyzed bifunctionalization of alkenes with anilines and HFIP has been achieved. Using readily available starting materials, a series of valuable complex highly functionalized 1,3-amino alcohols were isolated with moderate to good yields. Additionally, this protocol also presented a general and effective one-step procedure for the synthesis of 1,3-amino alcohols in an intermolecular manner.

引用

页数：6

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