A case of familial Mediterranean fever presenting with ankylosing spondylitis: A rare case-report

被引：0

作者：

Khalaji, Amirreza ^{[1
,2
]}

Jafarpour, Mehdi ^{[2
,3
]}

机构：

[1] Tabriz Univ Med Sci, Immunol Res Ctr, Tabriz, Iran

[2] Tabriz Univ Med Sci, Connect Tissue Dis Res Ctr, Tabriz, Iran

[3] Imam Reza Hosp, Connect Tissue Dis Res Ctr, Flat 1, Tabriz, Iran

来源：

CLINICAL CASE REPORTS | 2023年 / 11卷 / 11期

关键词：

ankylosing spondylitis; familial Mediterranean fever; HLA-B27; M694V; sacroiliitis; GENE;

D O I：

10.1002/ccr3.8197

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Key Clinical MessageThe association of familial Mediterranean fever and ankylosing spondylitis is rare, but it is essential to consider this diagnosis in patients with a history of FMF who develop symptoms of back pain or other rheumatologic conditions.AbstractFamilial Mediterranean fever (FMF) is an inherited inflammatory disorder characterized by recurrent fever episodes, abdominal pain, and arthralgia. Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects the spine's joints. The association of FMF and AS is rare. We report the case of a 22-year-old male patient with a history of FMF and a positive family history of FMF in his father, who presented with inflammatory back pain. The patient was found to have sacroiliitis on MRI, which is a characteristic feature of AS. The patient was negative for HLA-B27, a genetic marker often associated with AS. This case report highlights the importance of considering AS in patients with a history of FMF who develop back pain symptoms or other rheumatologic conditions. image

引用

页数：4

共 19 条

[1] High prevalence of spondyloarthritis and ankylosing spondylitis among familial Mediterranean fever patients and their first-degree relatives: further evidence for the connection [J].