Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study

被引:0
作者
Mohammedain, Shahd A. [1 ]
Badran, Saif [1 ,2 ]
Elzouki, AbdelNaser Y. [3 ]
Salim, Halla [3 ]
Chalaby, Ayesha [3 ]
Siddiqui, Mya [3 ]
Hussein, Yehia Y. [1 ]
Rahim, Hanan Abdul [4 ]
Thalib, Lukman [5 ]
Alam, Mohammed Fasihul [4 ]
Al-Badriyeh, Daoud [6 ]
Al-Maadeed, Sumaya [7 ]
Doi, Suhail A. R. [1 ]
机构
[1] Qatar Univ, Coll Med, Dept Populat Med, QU Hlth, Doha, Qatar
[2] Hamad Med Corp, Dept Plast Surg, Doha, Qatar
[3] Hamad Med Corp, Hamad Gen Hosp, Dept Internal Med, Doha, Qatar
[4] Qatar Univ, Coll Hlth Sci, Dept Publ Hlth, QU Hlth, Doha, Qatar
[5] Istanbul Aydin Univ, Fac Med, Dept Biostat, Istanbul, Turkiye
[6] Qatar Univ, Coll Pharm, QU Hlth, Doha, Qatar
[7] Qatar Univ, Coll Engn, Dept Comp Sci, Doha, Qatar
关键词
COVID-19; disease severity; prognosis; risk prediction; PNEUMONIA; PROGRESSION; MORTALITY; EXPLANATION; SARS-COV-2; SCORE;
D O I
10.2217/fvl-2023-0036
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Aim: This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients & methods/materials: Patients were recruited at their initial diagnosis at two facilities within Hamad Medical Corporation in Qatar. 356 adults were included for analysis. Predictors for progression of COVID-19 were all measured at disease onset and first contact with the health system. Results: The C statistic was 83% (95% CI: 78%-87%) and the calibration plot showed that the model was well-calibrated. Conclusion: The published prognostic model for the progression of COVID-19 infection showed satisfactory discrimination and calibration and the model is easy to apply in clinical practice.d
引用
收藏
页码:991 / 1000
页数:10
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