Organophotoelectrochemical silylation cyclization for the synthesis of silylated 3-CF3-2-oxindoles

被引：51

作者：

Wan, Qinhui ^{[1
,2
]}

Huang, Chen-Yin ^{[1
,2
]}

Hou, Zhong-Wei ^{[1
,2
]}

Jiang, Huajiang ^{[1
,2
]}

Wang, Lei ^{[1
,2
,3
,4
]}

机构：

[1] Taizhou Univ, Adv Res Inst, Jiaojiang 318000, Zhejiang, Peoples R China

[2] Taizhou Univ, Sch Pharmaceut Sci, Jiaojiang 318000, Zhejiang, Peoples R China

[3] Huaibei Normal Univ, Dept Chem, Huaibei 235000, Anhui, Peoples R China

[4] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2023年 / 10卷 / 14期

基金：

中国国家自然科学基金;

关键词：

RADICAL SILYLATION; N-ARYLACRYLAMIDES; CATALYSIS; BONDS;

D O I：

10.1039/d3qo00728f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An organophotoelectrochemical approach for silylation cyclization of CF3-substituted N-arylacrylamides with organosilanes has been developed. This photoelectrochemical method uses 9,10-phenanthrenequinone (PQ) as both a catalyst and a hydrogen atom transfer (HAT) reagent, and organosilanes as silyl radical precursors, obviating the need for oxidants or metal reagents. A series of silylated 3-CF3-2-oxindoles are prepared with satisfactory yields under simple and mild conditions.

引用

页码：3585 / 3590

页数：6

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