Synthesis And Pharmacological Validation Of Novel Neuroprotective Purinergic Receptor P2X4 Antagonists For The Treatment Of Ischemic Stroke

被引：0
|
作者：
Verma, Rajkumar
Toti, Kiran S.
Turro, Daylin Gamiotea
Wen, Zhiwei
Lewicki, Sarah
Jacobson, Kenneth
Liang, Bruce T.
机构：
来源：
STROKE | 2023年 / 54卷
关键词：
D O I：
10.1161/str.54.suppl_1.41
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A41
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Acute Treatment With Purinergic Receptor P2X4 Inhibitors Show Neuroprotective and Neuro-Rehabilitation Potential in Ischemic Stroke
    Verma, Rajkumar
    Srivastava, Pranay
    Cronin, Chunxia G.
    Scranton, Victoria
    Jacobson, Kenneth A.
    Liang, Bruce T.
    STROKE, 2019, 50
  • [2] Revealing the Novel Role of Purinergic Receptor P2X4 in Phagocytic Uptake After Ischemic Stroke
    Gamiotea-Turro, Daylin
    Cronin, Chunxia G.
    Yadav, Sanjeev Kumar
    Yadawa, Arun Kumar
    Cormier, Mary-Katherine
    Liang, Bruce T.
    Verma, Rajkumar
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2024, 13 (19):
  • [3] Phagocytic Potentials of Purinergic Receptor P2x4 Blockade After Ischemic Stroke
    Turro, Daylin Gamiotea
    Cronin, Chunxia
    Liang, Bruce T.
    Verma, Rajkumar
    STROKE, 2024, 55
  • [4] Neuroprotective and neuro-rehabilitative effects of acute purinergic receptor P2X4 (P2X4R) blockade after ischemic stroke
    Srivastava, Pranay
    Cronin, Chunxia G.
    Scranton, Victoria L.
    Jacobson, Kenneth A.
    Liang, Bruce T.
    Verma, Rajkumar
    EXPERIMENTAL NEUROLOGY, 2020, 329
  • [5] P2X4: A fast and sensitive purinergic receptor
    Suurvali, Jaanus
    Boudinot, Pierre
    Kanellopoulos, Jean
    Boudinot, Sirje Ruutel
    BIOMEDICAL JOURNAL, 2017, 40 (05) : 245 - 256
  • [6] Ivermectin is a selective modulator of the purinergic P2X4 receptor
    Godoy, MF
    Coddou, C
    Huidobro-Toro, JP
    PLACENTA, 2006, 27 (01) : A54 - A54
  • [7] The purinergic receptor P2X4 regulates liver fibrogenesis
    Guilcher, C. L.
    Garcin, I.
    Tebbi, A.
    Doignon, I.
    Tordjmann, T.
    Julien, B.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S45 - S45
  • [8] Deletion of the P2X4 receptor is neuroprotective acutely, but induces a depressive phenotype during recovery from ischemic stroke
    Verma, Rajkumar
    Cronin, Chunxia G.
    Hudobenko, Jacob
    Venna, Venugopal R.
    McCullough, Louise D.
    Liang, Bruce T.
    BRAIN BEHAVIOR AND IMMUNITY, 2017, 66 : 302 - 312
  • [9] Pharmacological characterisation of the human P2X4 receptor
    Fortuny-Gomez, Anna
    Fountain, Samuel
    BRITISH JOURNAL OF PHARMACOLOGY, 2020, 177 (11) : 2493 - 2494
  • [10] Interaction of Purinergic P2X4 and P2X7 Receptor Subunits
    Markwardt, Fritz
    Schneider, Markus
    Prudic, Kirsten
    Pippel, Anja
    Klapperstueck, Manuela
    Mueller, Christa
    Stolz, Michaela
    Schumacher, Michaela
    Schmalzing, Gunther
    BIOPHYSICAL JOURNAL, 2017, 112 (03) : 421A - 421A
12345