The Effectiveness and Safety of the Duodenal-Jejunal Bypass Liner (DJBL) for the Management of Obesity and Glycaemic Control: a Systematic Review and Meta-Analysis of Randomized Controlled Trials

被引：13
作者：
Yvamoto, Erika Yuki [1 ]
de Moura, Diogo Turiani Hourneaux [1 ]
Proenca, Igor Mendonca [1 ]
do Monte Junior, Epifanio Silvino [1 ]
Ribeiro, Igor Braga [1 ]
Ribas, Pedro Henrique Boraschi Vieira [1 ]
Hemerly, Matheus Candido [1 ]
de Oliveira, Victor Lira [1 ]
Sanchez-Luna, Sergio A. [2 ]
Bernardo, Wanderley Marques [1 ]
de Moura, Eduardo Guimaraes Hourneaux [1 ]
机构：
[1] Univ Sao Paulo, Dept Gastroenterol, Serv Endoscopia Gastrointestinal, Hosp Clin,Fac Med, Ave Dr Eneas Carvalho Aguiar 6 Andar,Bloco 3,Cerqu, BR-22505403 Sao Paulo, SP, Brazil
[2] Univ Alabama Birmingham, Basil I Hirschowitz Endoscop Ctr Excellence, Heersink Sch Med,Dept Internal Med, Div Gastroenterol & Hepatol, Birmingham, AL USA
来源：
OBESITY SURGERY | 2023年 / 33卷 / 02期
关键词：
Endoscopy; Duodenal-jejunal bypass liner; Obesity; Diabetes; Weight Loss; Glycaemic control; Bariatric surgery; Meta-analysis; Systematic review; ENDOBARRIER GASTROINTESTINAL LINER; TYPE-2; DIABETES-MELLITUS; WEIGHT-LOSS; MULTICENTER; CLASSIFICATION; EXCLUSION; EFFICACY; GRADE;
D O I：
10.1007/s11695-022-06379-0
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Introduction The duodenal-jejunal bypass liner (DJBL) is a less-invasive treatment of obesity and type 2 diabetes mellitus (T2DM). Methods This is a systematic review and meta-analysis including randomized clinical trials (RCTs) comparing DJBL versus sham or pharmacotherapies aiming to evaluate the effectiveness and safety of DJBL. Results Ten RCTs (681 patients) were included. The DJBL group showed superior excess weight loss (+ 11.4% [+ 7.75 to + 15.03%], p < 0.00001) and higher decrease in HbA1c compared to the control group (- 2.73 +/- 0.5 vs. - 1.73 +/- 0.4, p = 0.0001). Severe adverse events (SAEs) occurred in 19.7%. Conclusion The DJBL did not reach the ASGE/ASMBS thresholds for the treatment of obesity. However, it is important to state that many SAEs were not really severe. Therefore, we believe this therapy plays an important role in the management obesity and T2DM.
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收藏
页码：585 / 599
页数：15
相关论文
共 44 条
[1]   ASGE Bariatric Endoscopy Task Force systematic review and meta-analysis assessing the ASGE PIVI thresholds for adopting endoscopic bariatric therapies [J].
Abu Dayyeh, Barham K. ;
Kumar, Nitin ;
Edmundowicz, Steven A. ;
Jonnalagadda, Sreenivasa ;
Larsen, Michael ;
Sullivan, Shelby ;
Thompson, Christopher C. ;
Banerjee, Subhas .
GASTROINTESTINAL ENDOSCOPY, 2015, 82 (03) :425-+
[2]  
ASGE/ASMBS Task Force on Endoscopic Bariatric Therapy, SURG OBES RELAT DIS, V7, P672
[3]  
Benes M, 2019, DUODENOJEJUNAL BYPAS, DOI [10.1055/s-0039-1681326, DOI 10.1055/S-0039-1681326]
[4]   Weight reduction and improvement in diabetes by the duodenal-jejunal bypass liner: a 198 patient cohort study [J].
Betzel, Bark ;
Homan, Jens ;
Aarts, Edo O. ;
Janssen, Ignace M. C. ;
de Boer, Hans ;
Wahab, Peter J. ;
Groenen, Marcel J. M. ;
Berends, Frits J. .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2017, 31 (07) :2881-2891
[5]   Efficacy and Safety of the Duodeno-Jejunal Bypass Liner in Patients With Metabolic Syndrome A Multicenter Randomized Controlled Trial (ENDOMETAB) [J].
Caiazzo, Robert ;
Branche, Julien ;
Raverdy, Violeta ;
Czernichow, Sebastien ;
Carette, Claire ;
Robert, Maud ;
Disse, Emmanuel ;
Barthet, Marc ;
Cariou, Bertrand ;
Msika, Simon ;
Behal, Helene ;
Denies, Fanette ;
Dervaux, Benoit ;
Duhamel, Alain ;
Verkindt, Helene ;
Pattou, Francois .
ANNALS OF SURGERY, 2020, 272 (05) :696-702
[6]   Multidisciplinary Approach for Weight Regain-how to Manage this Challenging Condition: an Expert Review [J].
Cambi, Maria Paula Carlin ;
Baretta, Giorgio Alfredo Pedroso ;
Magro, Daniela De Oliveira ;
Boguszewski, Cesar Luiz ;
Ribeiro, Igor Braga ;
Jirapinyo, Pichamol ;
de Moura, Diogo Turiani Hourneaux .
OBESITY SURGERY, 2021, 31 (03) :1290-1303
[7]   Surgery for weight loss in adults [J].
Colquitt, Jill L. ;
Pickett, Karen ;
Loveman, Emma ;
Frampton, Geoff K. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, (08)
[8]   Minireview: Current status of endoscopic duodenal mucosal resurfacing [J].
Condello, Giancarlo ;
Chen, Chih-Yen .
OBESITY RESEARCH & CLINICAL PRACTICE, 2020, 14 (06) :504-507
[9]   Impact of Duodenal-Jejunal Exclusion on Satiety Hormones [J].
de Jonge, Charlotte ;
Rensen, Sander S. ;
Verdam, Froukje J. ;
Vincent, Royce P. ;
Bloom, Steve R. ;
Buurman, Wim A. ;
le Roux, Carel W. ;
Bouvy, Nicole D. ;
Greve, Jan Willem M. .
OBESITY SURGERY, 2016, 26 (03) :672-678
[10]   Six Months of Treatment with the Endoscopic Duodenal-Jejunal Bypass Liner Does Not Lead to Decreased Systemic Inflammation in Obese Patients with Type 2 Diabetes [J].
de Jonge, Charlotte ;
Rensen, Sander S. ;
D'Agnolo, Hedwig M. A. ;
Bouvy, Nicole D. ;
Buurman, Wim A. ;
Greve, Jan Willem M. .
OBESITY SURGERY, 2014, 24 (02) :337-341
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