Finding the right context of use for molecular transplant diagnostics in kidney allograft biopsies

被引：1

作者：

Mengel, Michael ^{[1
]}

Haas, Mark ^{[2
]}

机构：

[1] Univ Alberta, Dept Lab Med & Pathol, 5-412 ECHA, Edmonton, AB T6G 1C9, Canada

[2] Cedars Sinai Med Ctr, Dept Pathol & Lab Med, Los Angeles, CA USA

来源：

KIDNEY INTERNATIONAL | 2023年 / 104卷 / 03期

关键词：

REJECTION;

D O I：

10.1016/j.kint.2023.06.010

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Biopsy-based molecular diagnostics holds promise to increase diagnostic precision. In this issue of Kidney International, Beadle et al. describe a molecular classifier derived from the Banff Human Organ Transplant panel. This new molecular test specifically identifies biopsies associated with higher risk for allograft failure showing microvascular inflammation, but not considered diagnostic for antibody-mediated rejection by current Banff rules. This study marks a milestone toward defining a valuable context for use for biopsy-based molecular transplant diagnostics.

引用

页码：423 / 425

页数：3

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