Unusual Acute, Massive Lower Gastrointestinal Bleeding Secondary to a Proximal Jejunal Gastrointestinal Stromal Tumor: A Case Report

被引:0
作者
Alsulaiman, Ahlam A. [1 ]
AlAli, Mohammed N. [2 ]
Essa, Mohamed S. [2 ]
Alamri, Ossama [2 ]
Albdah, Abdullah M. [2 ]
Ahmad, Khaled S. [2 ]
机构
[1] Vis Coll, Coll Med, Fac Med, Riyadh, Saudi Arabia
[2] Prince Mohammed Bin Abdulaziz Hosp, Dept Surg, Minist Hlth MOH, Riyadh, Saudi Arabia
关键词
gist; small intestine; laparoscopic resection; jejunal gist; massive lower gi bleeding; IMATINIB; GIST; MANAGEMENT; DIAGNOSIS; RESECTION; ADJUVANT; SURGERY;
D O I
10.7759/cureus.35287
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The most common primary non-epithelial neoplasms of the gastrointestinal (GI) tract are gastrointestinal stromal tumors (GISTs). Ten percent (10%) of GISTs arise from the jejunum. Usually, patients complain of abdominal discomfort, but they may present with complications such as intestinal obstruction or bleeding. This report describes a 35-year-old male who presented with unusually massive, acute lower GI bleeding. After resuscitation and investigations (including a contrast-enhanced computed tomography of the abdomen and lower GI endoscopy), the patient underwent diagnostic laparoscopy and bowel resection of the affected section with anastomosis, and he had an eventful postoperative course. Studies suggest that GI bleeding in GIST occurs due to the ulceration and necrosis of the overlying mucosa caused by the pressure effect of the mass. Small-bowel GISTs are categorized based on their size. Many guidelines have advocated conservative management for small GISTs (<2 cm) that are in the jejunum. This patient has a rare case of a small jejunal GIST with a rare presentation of massive lower GI bleeding. A multidisciplinary approach is useful in managing such cases, and our case showed that laparoscopic intervention is a feasible option in a stable patient with massive lower GI bleeding.
引用
收藏
页数:7
相关论文
共 16 条
[1]   Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up [J].
Casali, P. G. ;
Abecassis, N. ;
Bauer, S. ;
Biagini, R. ;
Bielack, S. ;
Bonvalot, S. ;
Boukovinas, I. ;
Bovee, J. V. M. G. ;
Brodowicz, T. ;
Broto, J. M. ;
Buonadonna, A. ;
De Alava, E. ;
Dei Tos, A. P. ;
Del Muro, X. G. ;
Dileo, P. ;
Eriksson, M. ;
Fedenko, A. ;
Ferraresi, V. ;
Ferrari, A. ;
Ferrari, S. ;
Frezza, A. M. ;
Gasperoni, S. ;
Gelderblom, H. ;
Gil, T. ;
Grignani, G. ;
Gronchi, A. ;
Haas, R. L. ;
Hannu, A. ;
Hassan, B. ;
Hohenberger, P. ;
Issels, R. ;
Joensuu, H. ;
Jones, R. L. ;
Judson, I. ;
Jutte, P. ;
Kaal, S. ;
Kasper, B. ;
Kopeckova, K. ;
Krakorova, D. A. ;
Le Cesne, A. ;
Lugowska, I. ;
Merimsky, O. ;
Montemurro, M. ;
Pantaleo, M. A. ;
Piana, R. ;
Picci, P. ;
Piperno-Neumann, S. ;
Pousa, A. L. ;
Reichardt, P. ;
Robinson, M. H. .
ANNALS OF ONCOLOGY, 2018, 29 :68-78
[2]   A prospective epidemiological study of new incident GISTs during two consecutive years in Rhone Alpes region: incidence and molecular distribution of GIST in a European region [J].
Cassier, P. A. ;
Ducimetiere, F. ;
Lurkin, A. ;
Ranchere-Vince, D. ;
Scoazec, J-Y ;
Bringuier, P-P ;
Decouvelaere, A-V ;
Meeus, P. ;
Cellier, D. ;
Blay, J-Y ;
Ray-Coquard, I. .
BRITISH JOURNAL OF CANCER, 2010, 103 (02) :165-170
[3]   Laparoscopic Resection of Gastrointestinal Stromal Tumors: Safe, Efficient, and Comparable Oncologic Outcomes [J].
Chen, Yu-Hsien ;
Liu, Keng-Hao ;
Yeh, Chun-Nan ;
Hsu, Jun-Te ;
Liu, Yu-Yin ;
Tsai, Chun-Yi ;
Chiu, Cheng-Tang ;
Jan, Yi-Yin ;
Yeh, Ta-Sen .
JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, 2012, 22 (08) :758-763
[4]   Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial [J].
DeMatteo, Ronald P. ;
Ballman, Karla V. ;
Antonescu, Cristina R. ;
Maki, Robert G. ;
Pisters, Peter W. T. ;
Demetri, George D. ;
Blackstein, Martin E. ;
Blanke, Charles D. ;
von Mehren, Margaret ;
Brennan, Murray F. ;
Patel, Shreyaskumar ;
McCarter, Martin D. ;
Polikoff, Jonathan A. ;
Tan, Benjamin R. ;
Owzar, Kouros .
LANCET, 2009, 373 (9669) :1097-1104
[5]   Surgery and imatinib in the management of GIST: Emerging approaches to adjuvant and neoadjuvant therapy [J].
Eisenberg, BL ;
Judson, I .
ANNALS OF SURGICAL ONCOLOGY, 2004, 11 (05) :465-475
[6]   Computed tomography in gastrointestinal stromal tumors [J].
Ghanem, N ;
Altehoefer, C ;
Furtwängler, A ;
Winterer, J ;
Schäfer, O ;
Springer, O ;
Kotter, E ;
Langer, M .
EUROPEAN RADIOLOGY, 2003, 13 (07) :1669-1678
[7]   The Combination of Surgery and Imatinib in GIST: A Reality for Localized Tumors at High Risk, an Open Issue for Metastatic Ones [J].
Gronchi, Alessandro ;
Raut, Chandrajit P. .
ANNALS OF SURGICAL ONCOLOGY, 2012, 19 (04) :1051-1055
[8]   A jejunal gastrointestinal stromal tumor with massive gastrointestinal hemorrhage treated by emergency surgery: A case report [J].
Jablonska, Beata ;
Szmigiel, Pawel ;
Wosiewicz, Piotr ;
Baron, Jan ;
Szczesny-Karczewska, Weronika ;
Mrowiec, Slawomir .
MEDICINE, 2022, 101 (35) :E30098
[9]   Management of hemorrhage in gastrointestinal stromal tumors: a review [J].
Liu, Qi ;
Kong, Fanmin ;
Zhou, Jianping ;
Dong, Ming ;
Dong, Qi .
CANCER MANAGEMENT AND RESEARCH, 2018, 10 :735-743
[10]  
Maynard MA, 2014, NEW ENGL J MED, V370, P1327, DOI [10.1056/NEJMoa1308893, 10.1056/NEJMc1405198]