Challenges With Using a Weight-Based Approach to Bolus Fluid Dosing in Obese Critically Ill Patients Comment

被引:0
作者
Erstad, Brian L. [1 ]
Barletta, Jeffrey F. [2 ]
机构
[1] Univ Arizona, Dept Pharm Practice & Sci, 1295 N Martin, Tucson, AZ 85721 USA
[2] Midwestern Univ, Dept Pharm Practice, Coll Pharm, Glendale, AZ USA
关键词
critical care; fluid therapy; sepsis septic shock; fluid resuscitation; obesity; weight; SURVIVING SEPSIS CAMPAIGN; GOAL-DIRECTED RESUSCITATION; INTERNATIONAL GUIDELINES; SEPTIC SHOCK; BLOOD-VOLUME; MANAGEMENT; MORTALITY; STRATEGIES; THERAPY;
D O I
10.1177/10600280221125169
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
At least 30 mL/kg of crystalloid fluid administration within the first 3 hours of resuscitation is suggested by the current Surviving Sepsis Campaign guidelines for management of sepsis and septic shock. This commentary discusses the challenges with using a weight-based approach to bolus fluid dosing during the early phase of resuscitation of adult, obese patients. Based on the available literature, arguments can be made for the use of either ideal or adjusted body weight for weight-based fluid dosing, but there are concerns with fluid overload if using actual body weight to dose patients with more severe forms of obesity.
引用
收藏
页码:609 / 616
页数:8
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